TY - CHAP
T1 - Genetics of obsessive-compulsive disorder and tourette disorder
AU - Obsessive Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium
AU - Burton, Christie L.
AU - Barta, Csaba
AU - Cath, Danielle
AU - Geller, Daniel
AU - van den Heuvel, Odile A.
AU - Yao, Yin
AU - Eapen, Valsamma
AU - Grünblatt, Edna
AU - Zai, Gwyneth
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Obsessive-compulsive disorder (OCD) and Tourette disorder (TD) are neuropsychiatric disorders in which genetic factors play a substantial, and very often shared, role in both disorders. This chapter reviews the current literature on the genetics of OCD and TD, including genetic epidemiology within and across disorders, familiality, candidate gene studies, genome-wide association studies (GWAS), copy number variants (CNVs), imaging genetics, pharmacogenetics, epigenetics, and gene-environment interaction.
AB - Obsessive-compulsive disorder (OCD) and Tourette disorder (TD) are neuropsychiatric disorders in which genetic factors play a substantial, and very often shared, role in both disorders. This chapter reviews the current literature on the genetics of OCD and TD, including genetic epidemiology within and across disorders, familiality, candidate gene studies, genome-wide association studies (GWAS), copy number variants (CNVs), imaging genetics, pharmacogenetics, epigenetics, and gene-environment interaction.
KW - Epigenetics
KW - Gene-environment interaction
KW - Gene-gene interaction
KW - Genetics
KW - Imaging genetics
KW - Obsessive-compulsive disorder
KW - Pharmacogenetics
KW - Tourette’s disorder
UR - http://www.scopus.com/inward/record.url?scp=85081911075&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/B978-0-12-813176-3.00020-1
DO - https://doi.org/10.1016/B978-0-12-813176-3.00020-1
M3 - Chapter
SN - 9780128131770
SP - 239
EP - 252
BT - Personalized Psychiatry
PB - Elsevier
ER -