Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin

Patrick L. J. M. Zeeuwen; Thomas H. A. Ederveen; Danique A. van der Krieken; Hanna Niehues; Jos Boekhorst; Sanja Kezic; Daniëlle A. T. Hanssen; Marisol E. Otero; Ivonne M. J. J. van Vlijmen-Willems; Diana Rodijk-Olthuis; Denise Falcone; Ellen H. J. van den Bogaard; Marijke Kamsteeg; Heleen D. de Koning; Manon E. J. Zeeuwen-Franssen; Maurice A. M. van Steensel; Michiel Kleerebezem; Harro M. Timmerman; Sacha A. F. T. van Hijum; Joost Schalkwijk

doi:https://doi.org/10.1016/j.jaci.2016.09.017

Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin

Patrick L. J. M. Zeeuwen, Thomas H. A. Ederveen, Danique A. van der Krieken, Hanna Niehues, Jos Boekhorst, Sanja Kezic, Daniëlle A. T. Hanssen, Marisol E. Otero, Ivonne M. J. J. van Vlijmen-Willems, Diana Rodijk-Olthuis, Denise Falcone, Ellen H. J. van den Bogaard, Marijke Kamsteeg, Heleen D. de Koning, Manon E. J. Zeeuwen-Franssen, Maurice A. M. van Steensel, Michiel Kleerebezem, Harro M. Timmerman, Sacha A. F. T. van Hijum, Joost Schalkwijk

Research output: Contribution to journal › Comment/Letter to the editor › Academic

51 Citations (Scopus)

Abstract

Mutations in the filaggrin gene, which cause the skin disease ichthyosis vulgaris and are a genetic risk factor for atopic dermatitis, alter the cutaneous microbiome thereby affecting keratinocyte host defense responses following skin barrier disruption

Original language	English
Pages (from-to)	1368-1371
Journal	Journal of allergy and clinical immunology
Volume	139
Issue number	4
Early online date	2016
DOIs	https://doi.org/10.1016/j.jaci.2016.09.017
Publication status	Published - 2017

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https://doi.org/10.1016/j.jaci.2016.09.017

Cite this

Zeeuwen, P. L. J. M., Ederveen, T. H. A., van der Krieken, D. A., Niehues, H., Boekhorst, J., Kezic, S., Hanssen, D. A. T., Otero, M. E., van Vlijmen-Willems, I. M. J. J., Rodijk-Olthuis, D., Falcone, D., van den Bogaard, E. H. J., Kamsteeg, M., de Koning, H. D., Zeeuwen-Franssen, M. E. J., van Steensel, M. A. M., Kleerebezem, M., Timmerman, H. M., van Hijum, S. A. F. T., & Schalkwijk, J. (2017). Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin. Journal of allergy and clinical immunology, 139(4), 1368-1371. https://doi.org/10.1016/j.jaci.2016.09.017

@article{bf1a32d2f06446cbb087775cb0c52824,

title = "Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin",

abstract = "Mutations in the filaggrin gene, which cause the skin disease ichthyosis vulgaris and are a genetic risk factor for atopic dermatitis, alter the cutaneous microbiome thereby affecting keratinocyte host defense responses following skin barrier disruption",

author = "Zeeuwen, {Patrick L. J. M.} and Ederveen, {Thomas H. A.} and {van der Krieken}, {Danique A.} and Hanna Niehues and Jos Boekhorst and Sanja Kezic and Hanssen, {Dani{\"e}lle A. T.} and Otero, {Marisol E.} and {van Vlijmen-Willems}, {Ivonne M. J. J.} and Diana Rodijk-Olthuis and Denise Falcone and {van den Bogaard}, {Ellen H. J.} and Marijke Kamsteeg and {de Koning}, {Heleen D.} and Zeeuwen-Franssen, {Manon E. J.} and {van Steensel}, {Maurice A. M.} and Michiel Kleerebezem and Timmerman, {Harro M.} and {van Hijum}, {Sacha A. F. T.} and Joost Schalkwijk",

year = "2017",

doi = "https://doi.org/10.1016/j.jaci.2016.09.017",

language = "English",

volume = "139",

pages = "1368--1371",

journal = "Journal of allergy and clinical immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

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Zeeuwen, PLJM, Ederveen, THA, van der Krieken, DA, Niehues, H, Boekhorst, J, Kezic, S, Hanssen, DAT, Otero, ME, van Vlijmen-Willems, IMJJ, Rodijk-Olthuis, D, Falcone, D, van den Bogaard, EHJ, Kamsteeg, M, de Koning, HD, Zeeuwen-Franssen, MEJ, van Steensel, MAM, Kleerebezem, M, Timmerman, HM, van Hijum, SAFT & Schalkwijk, J 2017, 'Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin', Journal of allergy and clinical immunology, vol. 139, no. 4, pp. 1368-1371. https://doi.org/10.1016/j.jaci.2016.09.017

TY - JOUR

T1 - Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin

AU - Zeeuwen, Patrick L. J. M.

AU - Ederveen, Thomas H. A.

AU - van der Krieken, Danique A.

AU - Niehues, Hanna

AU - Boekhorst, Jos

AU - Kezic, Sanja

AU - Hanssen, Daniëlle A. T.

AU - Otero, Marisol E.

AU - van Vlijmen-Willems, Ivonne M. J. J.

AU - Rodijk-Olthuis, Diana

AU - Falcone, Denise

AU - van den Bogaard, Ellen H. J.

AU - Kamsteeg, Marijke

AU - de Koning, Heleen D.

AU - Zeeuwen-Franssen, Manon E. J.

AU - van Steensel, Maurice A. M.

AU - Kleerebezem, Michiel

AU - Timmerman, Harro M.

AU - van Hijum, Sacha A. F. T.

AU - Schalkwijk, Joost

PY - 2017

Y1 - 2017

N2 - Mutations in the filaggrin gene, which cause the skin disease ichthyosis vulgaris and are a genetic risk factor for atopic dermatitis, alter the cutaneous microbiome thereby affecting keratinocyte host defense responses following skin barrier disruption

AB - Mutations in the filaggrin gene, which cause the skin disease ichthyosis vulgaris and are a genetic risk factor for atopic dermatitis, alter the cutaneous microbiome thereby affecting keratinocyte host defense responses following skin barrier disruption

U2 - https://doi.org/10.1016/j.jaci.2016.09.017

DO - https://doi.org/10.1016/j.jaci.2016.09.017

M3 - Comment/Letter to the editor

C2 - 27725187

SN - 0091-6749

VL - 139

SP - 1368

EP - 1371

JO - Journal of allergy and clinical immunology

JF - Journal of allergy and clinical immunology

IS - 4

ER -