Head Trauma and Alzheimer's Disease: A Case Report and Review of the Literature

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The authors describe a case of a 55-year-old woman who was diagnosed with Alzheimer's disease 1.5 years after a car accident in which she experienced a mild concussion. Extensive history taking disclosed no cognitive changes prior to the car accident. The case is discussed in view of the inflammation hypothesis regarding Alzheimer's disease and the role of the apolipoprotein E4 genotype of the patient.

Original languageEnglish
Title of host publicationHandbook of Traumatic Brain Injury and Neurodegeneration
EditorsRudy J. Castellani
PublisherIOS Press
Number of pages5
ISBN (Electronic)9781643680644
Publication statusPublished - 1 Jan 2020

Publication series

NameAdvances in Alzheimer's Disease


  • Alzheimer's disease
  • ApoE
  • amyloid
  • atrophy
  • cholinesterase inhibitors
  • head trauma
  • inflammation

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