Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist

C. Grootscholten; G. Ligtenberg; R. H. W. M. Derksen; K. M. G. Schreurs; J. W. de Glas-Vos; E. C. Hagen; A. W. L. van den Wall Bake; T. W. J. Huizinga; F. H. J. van den Hoogen; M. Bijl; J. C. van Houwelingen; F. J. Snoek; J. H. M. Berden

doi:https://doi.org/10.1023/A:1025176407776

Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist

C. Grootscholten, G. Ligtenberg, R. H. W. M. Derksen, K. M. G. Schreurs, J. W. de Glas-Vos, E. C. Hagen, A. W. L. van den Wall Bake, T. W. J. Huizinga, F. H. J. van den Hoogen, M. Bijl, J. C. van Houwelingen, F. J. Snoek, J. H. M. Berden

Research output: Contribution to journal › Article › Academic › peer-review

73 Citations (Scopus)

Abstract

Reliable and sensitive measures are needed to evaluate the quality of life (QoL) in patients with systemic lupus erythematosus (SLE). No lupus specific questionnaires are available. This study describes the development and validation of a disease-specific questionnaire for lupus patients, which assesses the presence and burden of 38 disease- and treatment-related symptoms: the SLE Symptom Checklist (SSC). Reliability and reproducibility were tested in respectively 87 and 28 stable SLE patients. The internal consistency (Cronbach's alpha coefficients 0.89) and test-retest reliability (Pearson product-moment correlation coefficient between 0.67 and 0.87) were satisfactory. Concurrent validity was supported by significant, but moderate correlations with other measures of subjective well-being and functional status. Responsiveness was measured in 17 patients with lupus nephritis treated with cyclophosphamide, at start of therapy and 1 year thereafter. A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes

Original language	English
Pages (from-to)	635-644
Number of pages	10
Journal	Quality of life research
Volume	12
Issue number	6
DOIs	https://doi.org/10.1023/A:1025176407776
Publication status	Published - 1 Sept 2003

Keywords

Health status
Quality of life
Questionnaire
Systemic Lupus Erythematosus
Validation

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Grootscholten, C., Ligtenberg, G., Derksen, R. H. W. M., Schreurs, K. M. G., de Glas-Vos, J. W., Hagen, E. C., van den Wall Bake, A. W. L., Huizinga, T. W. J., van den Hoogen, F. H. J., Bijl, M., van Houwelingen, J. C., Snoek, F. J., & Berden, J. H. M. (2003). Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist. Quality of life research, 12(6), 635-644. https://doi.org/10.1023/A:1025176407776

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title = "Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist",

abstract = "Reliable and sensitive measures are needed to evaluate the quality of life (QoL) in patients with systemic lupus erythematosus (SLE). No lupus specific questionnaires are available. This study describes the development and validation of a disease-specific questionnaire for lupus patients, which assesses the presence and burden of 38 disease- and treatment-related symptoms: the SLE Symptom Checklist (SSC). Reliability and reproducibility were tested in respectively 87 and 28 stable SLE patients. The internal consistency (Cronbach's alpha coefficients 0.89) and test-retest reliability (Pearson product-moment correlation coefficient between 0.67 and 0.87) were satisfactory. Concurrent validity was supported by significant, but moderate correlations with other measures of subjective well-being and functional status. Responsiveness was measured in 17 patients with lupus nephritis treated with cyclophosphamide, at start of therapy and 1 year thereafter. A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes",

keywords = "Health status, Quality of life, Questionnaire, Systemic Lupus Erythematosus, Validation",

author = "C. Grootscholten and G. Ligtenberg and Derksen, {R. H. W. M.} and Schreurs, {K. M. G.} and {de Glas-Vos}, {J. W.} and Hagen, {E. C.} and {van den Wall Bake}, {A. W. L.} and Huizinga, {T. W. J.} and {van den Hoogen}, {F. H. J.} and M. Bijl and {van Houwelingen}, {J. C.} and Snoek, {F. J.} and Berden, {J. H. M.}",

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Grootscholten, C, Ligtenberg, G, Derksen, RHWM, Schreurs, KMG, de Glas-Vos, JW, Hagen, EC, van den Wall Bake, AWL, Huizinga, TWJ, van den Hoogen, FHJ, Bijl, M, van Houwelingen, JC, Snoek, FJ & Berden, JHM 2003, 'Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist', Quality of life research, vol. 12, no. 6, pp. 635-644. https://doi.org/10.1023/A:1025176407776

Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist. / Grootscholten, C.; Ligtenberg, G.; Derksen, R. H. W. M. et al.
In: Quality of life research, Vol. 12, No. 6, 01.09.2003, p. 635-644.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist

T2 - Development and validation of a lupus specific symptom checklist

AU - Grootscholten, C.

AU - Ligtenberg, G.

AU - Derksen, R. H. W. M.

AU - Schreurs, K. M. G.

AU - de Glas-Vos, J. W.

AU - Hagen, E. C.

AU - van den Wall Bake, A. W. L.

AU - Huizinga, T. W. J.

AU - van den Hoogen, F. H. J.

AU - Bijl, M.

AU - van Houwelingen, J. C.

AU - Snoek, F. J.

AU - Berden, J. H. M.

PY - 2003/9/1

Y1 - 2003/9/1

N2 - Reliable and sensitive measures are needed to evaluate the quality of life (QoL) in patients with systemic lupus erythematosus (SLE). No lupus specific questionnaires are available. This study describes the development and validation of a disease-specific questionnaire for lupus patients, which assesses the presence and burden of 38 disease- and treatment-related symptoms: the SLE Symptom Checklist (SSC). Reliability and reproducibility were tested in respectively 87 and 28 stable SLE patients. The internal consistency (Cronbach's alpha coefficients 0.89) and test-retest reliability (Pearson product-moment correlation coefficient between 0.67 and 0.87) were satisfactory. Concurrent validity was supported by significant, but moderate correlations with other measures of subjective well-being and functional status. Responsiveness was measured in 17 patients with lupus nephritis treated with cyclophosphamide, at start of therapy and 1 year thereafter. A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes

AB - Reliable and sensitive measures are needed to evaluate the quality of life (QoL) in patients with systemic lupus erythematosus (SLE). No lupus specific questionnaires are available. This study describes the development and validation of a disease-specific questionnaire for lupus patients, which assesses the presence and burden of 38 disease- and treatment-related symptoms: the SLE Symptom Checklist (SSC). Reliability and reproducibility were tested in respectively 87 and 28 stable SLE patients. The internal consistency (Cronbach's alpha coefficients 0.89) and test-retest reliability (Pearson product-moment correlation coefficient between 0.67 and 0.87) were satisfactory. Concurrent validity was supported by significant, but moderate correlations with other measures of subjective well-being and functional status. Responsiveness was measured in 17 patients with lupus nephritis treated with cyclophosphamide, at start of therapy and 1 year thereafter. A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes

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KW - Quality of life

KW - Questionnaire

KW - Systemic Lupus Erythematosus

KW - Validation

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DO - https://doi.org/10.1023/A:1025176407776

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SN - 0962-9343

VL - 12

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Grootscholten C, Ligtenberg G, Derksen RHWM, Schreurs KMG, de Glas-Vos JW, Hagen EC et al. Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist. Quality of life research. 2003 Sept 1;12(6):635-644. doi: https://doi.org/10.1023/A:1025176407776

Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist: Development and validation of a lupus specific symptom checklist

Abstract

Keywords

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