TY - JOUR
T1 - High levels of antenatal maternal anxiety are associated with altered cognitive control in five-year-old children
AU - Loomans, Eva Margarita
AU - van der Stelt, O.
AU - van Eijsden, M.
AU - Gemke, R. J. B. J.
AU - Vrijkotte, T. G. M.
AU - van den Bergh, B. R. H.
PY - 2012
Y1 - 2012
N2 - This longitudinal prospective study examined the relation between maternal anxiety during pregnancy and specific aspects of children's cognitive functioning at age five. Antenatal maternal state-anxiety was measured around the 16th week of pregnancy. Children's neurocognitive functioning was examined using a simple reaction time (RT) task, and a choice RT task. Multiple regression analyses in the total sample (N?=?922) showed that antenatal anxiety was positively related to children's intra-individual variability in RT in the simple task. In a subsample (n?=?100) of women with state-anxiety scores above the 90th percentile, antenatal anxiety was positively associated with mean RT and intra-individual variability in RT in the incompatible trials of the choice RT task. In addition, in this subsample of highly anxious mothers we found a significant positive association in boys but not in girls, between prenatal maternal anxiety and intra-individual variability in RT in the simple task. (c) 2011 Wiley Periodicals, Inc. Dev Psychobiol 54:441450, 2012
AB - This longitudinal prospective study examined the relation between maternal anxiety during pregnancy and specific aspects of children's cognitive functioning at age five. Antenatal maternal state-anxiety was measured around the 16th week of pregnancy. Children's neurocognitive functioning was examined using a simple reaction time (RT) task, and a choice RT task. Multiple regression analyses in the total sample (N?=?922) showed that antenatal anxiety was positively related to children's intra-individual variability in RT in the simple task. In a subsample (n?=?100) of women with state-anxiety scores above the 90th percentile, antenatal anxiety was positively associated with mean RT and intra-individual variability in RT in the incompatible trials of the choice RT task. In addition, in this subsample of highly anxious mothers we found a significant positive association in boys but not in girls, between prenatal maternal anxiety and intra-individual variability in RT in the simple task. (c) 2011 Wiley Periodicals, Inc. Dev Psychobiol 54:441450, 2012
U2 - https://doi.org/10.1002/dev.20606
DO - https://doi.org/10.1002/dev.20606
M3 - Article
C2 - 21953508
SN - 0012-1630
VL - 54
SP - 441
EP - 450
JO - Developmental Psychobiology
JF - Developmental Psychobiology
IS - 4
ER -