High-resolution segmented EPI in a motor task fMRI study

F. G C Hoogenraad, P. J W Pouwels, M. B M Hofman, S. A R B Rombouts, C. Lavini, M. O. Leach, E. M. Haacke

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38 Citations (Scopus)


A high-resolution gradient echo, multi-slice segmented echo planar imaging method was used for functional MRI (fMRI) using a motor task at 1.5 Tesla. Functional images with an in-plane resolution of 1 mm and slice thickness of 4 mm were obtained with good white-gray matter contrast. The multi-shot approach, combined with a short total readout period of 82 ms, limits blurring effects for short T2/* tissues (such as gray matter), assuring truly high-resolution images. In all subjects, motor functions were clearly depicted in the contralateral central sulcus over several slices and sometimes activation was detected in the supplementary motor area and/or ipsilateral central sulcus. The average signal change of 11 ± 3% was much higher than in standard low-resolution fMRI EPI experiments, as a result of larger relative blood fractions. (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)405-409
Number of pages5
JournalMagnetic Resonance Imaging
Issue number4
Publication statusPublished - 1 May 2000


  • FMRI
  • High-resolution
  • Motor cortex
  • Segmented-EPI

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