Abstract
A high-resolution gradient echo, multi-slice segmented echo planar imaging method was used for functional MRI (fMRI) using a motor task at 1.5 Tesla. Functional images with an in-plane resolution of 1 mm and slice thickness of 4 mm were obtained with good white-gray matter contrast. The multi-shot approach, combined with a short total readout period of 82 ms, limits blurring effects for short T2/* tissues (such as gray matter), assuring truly high-resolution images. In all subjects, motor functions were clearly depicted in the contralateral central sulcus over several slices and sometimes activation was detected in the supplementary motor area and/or ipsilateral central sulcus. The average signal change of 11 ± 3% was much higher than in standard low-resolution fMRI EPI experiments, as a result of larger relative blood fractions. (C) 2000 Elsevier Science Inc.
Original language | English |
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Pages (from-to) | 405-409 |
Number of pages | 5 |
Journal | Magnetic Resonance Imaging |
Volume | 18 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 May 2000 |
Keywords
- FMRI
- High-resolution
- Motor cortex
- Segmented-EPI