TY - JOUR
T1 - Higher glucose variability in type 1 than in type 2 diabetes patients admitted to the intensive care unit: A retrospective cohort study
AU - Sechterberger, Marjolein K.
AU - van Steen, Sigrid C. J.
AU - Boerboom, Esther M. N.
AU - van der Voort, Peter H. J.
AU - Bosman, Rob J.
AU - Hoekstra, Joost B. L.
AU - DeVries, J. Hans
PY - 2017
Y1 - 2017
N2 - Purpose: Although the course of disease of type 1 and type 2 diabetes differs, the distinction is rarely made when patients are admitted to the intensive care unit (ICU). Here, we report patient- and admission-related characteristics in relation to glycemic measures of patients with type I and type 2 diabetes admitted to the ICU. Materials and methods: A retrospective chart review was performed of 1574 patients with diabetes admitted between 2004 and 2011 to our ICU. Glycemic measures included mean glucose, the incidence of hypoglycemia and hyperglycemia, percentage of glucose values in/below/above target, and glucose variability. The ICU and hospital mortality were secondary outcomes. Results: We classified 2% (n = 27) of patients as having type 1 diabetes and 98% (n = 1547) as having type 2 diabetes. Patients with type I diabetes were significantly younger, had a lower body mass index, and were more frequently admitted to the ICU for medical diagnoses. No differences in glycemic measures were found, apart from a 20% higher glucose variability in the type 1 diabetes group. Conclusions: Patients with type 1 diabetes showed a higher glucose variability, but overall glycemic control was not different between patients with type 1 and type 2 diabetes. Very few diabetes patients admitted to the ICU have type 1 diabetes. (C) 2016 Elsevier Inc. All rights reserved
AB - Purpose: Although the course of disease of type 1 and type 2 diabetes differs, the distinction is rarely made when patients are admitted to the intensive care unit (ICU). Here, we report patient- and admission-related characteristics in relation to glycemic measures of patients with type I and type 2 diabetes admitted to the ICU. Materials and methods: A retrospective chart review was performed of 1574 patients with diabetes admitted between 2004 and 2011 to our ICU. Glycemic measures included mean glucose, the incidence of hypoglycemia and hyperglycemia, percentage of glucose values in/below/above target, and glucose variability. The ICU and hospital mortality were secondary outcomes. Results: We classified 2% (n = 27) of patients as having type 1 diabetes and 98% (n = 1547) as having type 2 diabetes. Patients with type I diabetes were significantly younger, had a lower body mass index, and were more frequently admitted to the ICU for medical diagnoses. No differences in glycemic measures were found, apart from a 20% higher glucose variability in the type 1 diabetes group. Conclusions: Patients with type 1 diabetes showed a higher glucose variability, but overall glycemic control was not different between patients with type 1 and type 2 diabetes. Very few diabetes patients admitted to the ICU have type 1 diabetes. (C) 2016 Elsevier Inc. All rights reserved
U2 - https://doi.org/10.1016/j.jcrc.2016.12.021
DO - https://doi.org/10.1016/j.jcrc.2016.12.021
M3 - Article
C2 - 28063297
SN - 0883-9441
VL - 38
SP - 300
EP - 303
JO - Journal of Critical Care
JF - Journal of Critical Care
ER -