TY - JOUR
T1 - HIGHER LARYNGEAL PRESERVATION RATE AFTER CO(2) LASER SURGERY COMPARED WITH RADIOTHERAPY IN T1A GLOTTIC LARYNGEAL CARCINOMA
AU - Schrijvers, Michiel L.
AU - van Riel, Eva L.
AU - Langendijk, Johannes A.
AU - Dikkers, Frederik G.
AU - Schuuring, Ed
AU - van der Wal, Jacqueline E.
AU - van der Laan, Bernard F. A. M.
PY - 2009
Y1 - 2009
N2 - Background. Clinical outcome of endoscopic CO(2) laser surgery and radiotherapy in early-stage glottic laryngeal carcinoma is difficult to compare because of differences in treatment selection and patient groups. Therefore, we compared local control, overall survival, and laryngeal preservation in a homogenous group of patients with T1a glottic carcinoma with normal/diminished mucosal wave treated with either CO(2) laser surgery or radiotherapy. Methods. Retrospective survival analysis was performed on 100 patients with T1a glottic carcinoma treated with CO(2) laser surgery (n = 49) or radiotherapy (n = 51), diagnosed at the University Medical Center Groningen between 1990 and 2004. Results. No significant differences in local control and overall survival were found. Ultimate 5-year laryngeal preservation was significantly better in the CO(2) laser surgery group (95% vs 77%, p = .043). Conclusion. Patients with T1a glottic carcinoma with normal/diminished mucosal wave treated with CO(2) laser surgery had a significantly better laryngeal preservation rate than patients treated with radiotherapy. (c) 2009 Wiley Periodicals, Inc. Head Neck 31: 759-764, 2009
AB - Background. Clinical outcome of endoscopic CO(2) laser surgery and radiotherapy in early-stage glottic laryngeal carcinoma is difficult to compare because of differences in treatment selection and patient groups. Therefore, we compared local control, overall survival, and laryngeal preservation in a homogenous group of patients with T1a glottic carcinoma with normal/diminished mucosal wave treated with either CO(2) laser surgery or radiotherapy. Methods. Retrospective survival analysis was performed on 100 patients with T1a glottic carcinoma treated with CO(2) laser surgery (n = 49) or radiotherapy (n = 51), diagnosed at the University Medical Center Groningen between 1990 and 2004. Results. No significant differences in local control and overall survival were found. Ultimate 5-year laryngeal preservation was significantly better in the CO(2) laser surgery group (95% vs 77%, p = .043). Conclusion. Patients with T1a glottic carcinoma with normal/diminished mucosal wave treated with CO(2) laser surgery had a significantly better laryngeal preservation rate than patients treated with radiotherapy. (c) 2009 Wiley Periodicals, Inc. Head Neck 31: 759-764, 2009
U2 - https://doi.org/10.1002/hed.21027
DO - https://doi.org/10.1002/hed.21027
M3 - Article
C2 - 19260127
SN - 1043-3074
VL - 31
SP - 759
EP - 764
JO - Head & neck
JF - Head & neck
IS - 6
ER -