TY - JOUR
T1 - How i treat cancer-associated venous thromboembolism
AU - Kraaijpoel, Noémie
AU - Carrier, Marc
PY - 2019
Y1 - 2019
N2 - Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is a common complication of cancer and is associated with significant morbidity and mortality. Several cancer-related risk factors contribute to the development of VTE including cancer type and stage, chemotherapy, surgery, and patient-related factors such as advanced age and immobilization. Patients with cancer frequently undergo diagnostic imaging scans for cancer staging and treatment response evaluation, which is increasing the underlying risk of VTE detection. The management of cancer-associated VTE is challenging. Over the years, important advances have been made and, recently, randomized controlled trials have been published helping clinicians' management of this patient population. In this review, we will discuss common cancer-associated VTE scenarios and critically review available evidence to guide treatment decisions.
AB - Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is a common complication of cancer and is associated with significant morbidity and mortality. Several cancer-related risk factors contribute to the development of VTE including cancer type and stage, chemotherapy, surgery, and patient-related factors such as advanced age and immobilization. Patients with cancer frequently undergo diagnostic imaging scans for cancer staging and treatment response evaluation, which is increasing the underlying risk of VTE detection. The management of cancer-associated VTE is challenging. Over the years, important advances have been made and, recently, randomized controlled trials have been published helping clinicians' management of this patient population. In this review, we will discuss common cancer-associated VTE scenarios and critically review available evidence to guide treatment decisions.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060533139&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30478093
U2 - https://doi.org/10.1182/blood-2018-08-835595
DO - https://doi.org/10.1182/blood-2018-08-835595
M3 - Article
C2 - 30478093
SN - 0006-4971
VL - 133
SP - 291
EP - 298
JO - Blood
JF - Blood
IS - 4
ER -