Abstract
Severe or even mild hyperhomocysteinaemia can cause a wide range of neurological problems. In recent years its vascular complications, including cerebral stroke, in children and young adults have gained special interest, because hyperhomocysteinaemia is treatable and recurrence of vascular incidents may be preventable. Current knowledge about biochemical mechanisms leading to hyperhomocysteinaemia, the pathogenesis of vascular pathology and neurological disfunction, and the various patterns of cerebral damage are reviewed. The significance of MRI in diagnosis, follow-up and research on hyperhomocysteinaemia is discussed.
Original language | English |
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Pages (from-to) | 403-411 |
Number of pages | 9 |
Journal | Neuroradiology |
Volume | 37 |
Issue number | 5 |
DOIs | |
Publication status | Published - Jul 1995 |
Keywords
- Demyelination
- Hyperhomocysteinaemia
- Magnetic resonance imaging
- Premature arteriosclerosis