TY - JOUR
T1 - Hypocalciëmisch delier door magnesiumsulfaatbehandeling bij een zwangere met preëclampsie
AU - Ganzevoort, J. W.
AU - Hoogerwaard, E. M.
AU - van der Post, J. A. M.
PY - 2002
Y1 - 2002
N2 - A 34-year-old pregnant patient, admitted with severe pre-eclampsia and the 'haemolysis, elevated liver enzymes, low platelets' (HELLP) syndrome at 31 weeks gestational age, was treated with magnesium sulphate for imminent eclampsia. The further management was aimed at prolonging gestation. During treatment, a delirium developed with myoclonus. As the foetal condition deteriorated, caesarean section was performed. Afterwards, the delirium proved to have been due to hypocalcaemia. After appropriate treatment the patient recovered. In pre-eclampsia, the calcium metabolism is disturbed. Hypermagnesaemia inhibits parathyroid hormone secretion and can therefore cause hypocalcaemia. In rare cases, this may cause a delirium, which is unusual in pre-eclampsia. If the clinical (neurological) picture in a pregnant woman with severe pre-eclampsia, who is receiving treatment with magnesium sulphate, is not fully understood, hypocalcaemia should be considered
AB - A 34-year-old pregnant patient, admitted with severe pre-eclampsia and the 'haemolysis, elevated liver enzymes, low platelets' (HELLP) syndrome at 31 weeks gestational age, was treated with magnesium sulphate for imminent eclampsia. The further management was aimed at prolonging gestation. During treatment, a delirium developed with myoclonus. As the foetal condition deteriorated, caesarean section was performed. Afterwards, the delirium proved to have been due to hypocalcaemia. After appropriate treatment the patient recovered. In pre-eclampsia, the calcium metabolism is disturbed. Hypermagnesaemia inhibits parathyroid hormone secretion and can therefore cause hypocalcaemia. In rare cases, this may cause a delirium, which is unusual in pre-eclampsia. If the clinical (neurological) picture in a pregnant woman with severe pre-eclampsia, who is receiving treatment with magnesium sulphate, is not fully understood, hypocalcaemia should be considered
M3 - Article
C2 - 12190013
SN - 0028-2162
VL - 146
SP - 1453
EP - 1456
JO - Nederlands Tijdschrift voor Geneeskunde
JF - Nederlands Tijdschrift voor Geneeskunde
IS - 31
ER -