TY - JOUR
T1 - IAP/APA evidence-based guidelines for the management of acute pancreatitis
AU - AUTHOR GROUP
AU - Besselink, Marc
AU - van Santvoort, Hjalmar
AU - Freeman, Martin
AU - Gardner, Timothy
AU - Mayerle, Julia
AU - Vege, Santhi Swaroop
AU - Werner, Jens
AU - Banks, Peter
AU - McKay, Colin
AU - Fernandez-del Castillo, Carlos
AU - French, Jeremy
AU - Gooszen, Hein
AU - Johnson, Colin
AU - Sarr, Mike
AU - Takada, Tadahiro
AU - Windsor, John
AU - Saluja, Ashok
AU - Liddle, Rodger
AU - Papachristou, Georgios
AU - Singh, Vijay
AU - Rünzi, Michael
AU - Wu, Bechien
AU - Singh, Vikesh
AU - Bollen, Thomas
AU - Morgan, Desiree
AU - Mortele, Koenraad
AU - Mittal, Anubhav
AU - En-qiang, Mao
AU - de Waele, Jan
AU - Petrov, Maxim
AU - Dellinger, Patchen
AU - Lerch, Markus M.
AU - Anderson, Roland
AU - McClave, Stephen
AU - Hartwig, Werner
AU - Bruno, Marco
AU - Oria, Alejandro
AU - Baron, Todd
AU - Castillo, Carlos Fernandez-Del
AU - Fagenholz, Peter
AU - Horvath, Karen
AU - van Baal, Mark
AU - Nealon, William
AU - Andren-Sandberg, Ake
AU - Bakker, Olaf
AU - Bassi, Claudio
AU - Buchler, Markus
AU - Boermeester, Marja
AU - Bradley, Ed
AU - Fockens, Paul
PY - 2013
Y1 - 2013
N2 - There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these guidelines using an evidence-based approach. Twelve multidisciplinary review groups performed systematic literature reviews to answer 38 predefined clinical questions. Recommendations were graded using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The review groups presented their recommendations during the 2012 joint IAP/APA meeting. At this one-day, interactive conference, relevant remarks were voiced and overall agreement on each recommendation was quantified using plenary voting. The 38 recommendations covered 12 topics related to the clinical management of acute pancreatitis: A) diagnosis of acute pancreatitis and etiology, B) prognostication/predicting severity, C) imaging, D) fluid therapy, E) intensive care management, F) preventing infectious complications, G) nutritional support, H) biliary tract management, I) indications for intervention in necrotizing pancreatitis, J) timing of intervention in necrotizing pancreatitis, K) intervention strategies in necrotizing pancreatitis, and L) timing of cholecystectomy. Using the GRADE system, 21 of the 38 (55%) recommendations, were rated as 'strong' and plenary voting revealed 'strong agreement' for 34 (89%) recommendations. The 2012 IAP/APA guidelines provide recommendations concerning key aspects of medical and surgical management of acute pancreatitis based on the currently available evidence. These recommendations should serve as a reference standard for current management and guide future clinical research on acute pancreatitis
AB - There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these guidelines using an evidence-based approach. Twelve multidisciplinary review groups performed systematic literature reviews to answer 38 predefined clinical questions. Recommendations were graded using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The review groups presented their recommendations during the 2012 joint IAP/APA meeting. At this one-day, interactive conference, relevant remarks were voiced and overall agreement on each recommendation was quantified using plenary voting. The 38 recommendations covered 12 topics related to the clinical management of acute pancreatitis: A) diagnosis of acute pancreatitis and etiology, B) prognostication/predicting severity, C) imaging, D) fluid therapy, E) intensive care management, F) preventing infectious complications, G) nutritional support, H) biliary tract management, I) indications for intervention in necrotizing pancreatitis, J) timing of intervention in necrotizing pancreatitis, K) intervention strategies in necrotizing pancreatitis, and L) timing of cholecystectomy. Using the GRADE system, 21 of the 38 (55%) recommendations, were rated as 'strong' and plenary voting revealed 'strong agreement' for 34 (89%) recommendations. The 2012 IAP/APA guidelines provide recommendations concerning key aspects of medical and surgical management of acute pancreatitis based on the currently available evidence. These recommendations should serve as a reference standard for current management and guide future clinical research on acute pancreatitis
U2 - https://doi.org/10.1016/j.pan.2013.07.063
DO - https://doi.org/10.1016/j.pan.2013.07.063
M3 - Article
C2 - 24054878
SN - 1424-3903
VL - 13
SP - e1-15
JO - Pancreatology
JF - Pancreatology
IS - 4 Suppl 2
ER -