Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects

A. M. Witteman; J. H. Akkerdaas; J. van Leeuwen; J. S. van der Zee; R. C. Aalberse

doi:https://doi.org/10.1159/000236803

Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects

A. M. Witteman, J. H. Akkerdaas, J. van Leeuwen, J. S. van der Zee, R. C. Aalberse

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Abstract

A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients

Original language	English
Pages (from-to)	56-61
Journal	International archives of allergy and immunology
Volume	105
Issue number	1
DOIs	https://doi.org/10.1159/000236803
Publication status	Published - 1994

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https://doi.org/10.1159/000236803

Cite this

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title = "Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects",

abstract = "A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients",

author = "Witteman, {A. M.} and Akkerdaas, {J. H.} and {van Leeuwen}, J. and {van der Zee}, {J. S.} and Aalberse, {R. C.}",

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AU - Witteman, A. M.

AU - Akkerdaas, J. H.

AU - van Leeuwen, J.

AU - van der Zee, J. S.

AU - Aalberse, R. C.

PY - 1994

Y1 - 1994

N2 - A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients

AB - A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients

U2 - https://doi.org/10.1159/000236803

DO - https://doi.org/10.1159/000236803

M3 - Article

C2 - 8086829

SN - 1018-2438

VL - 105

SP - 56

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