TY - JOUR
T1 - Identification of a novel human rhinovirus C type by antibody capture VIDISCA-454
AU - Jazaeri Farsani, Seyed Mohammad
AU - Oude Munnink, Bas B.
AU - Canuti, Marta
AU - Deijs, Martin
AU - Cotten, Matthew
AU - Jebbink, Maarten F.
AU - Verhoeven, Joost
AU - Kellam, Paul
AU - Loens, Katherine
AU - Goossens, Herman
AU - Ieven, Margareta
AU - van der Hoek, Lia
PY - 2015
Y1 - 2015
N2 - Causative agents for more than 30 percent of respiratory infections remain unidentified, suggesting that unknown respiratory pathogens might be involved. In this study, antibody capture VIDISCA-454 (virus discovery cDNA-AFLP combined with Roche 454 high-throughput sequencing) resulted in the discovery of a novel type of rhinovirus C (RV-C). The virus has an RNA genome of at least 7054 nt and carries the characteristics of rhinovirus C species. The gene encoding viral protein 1, which is used for typing, has only 81% nucleotide sequence identity with the closest known RV-C type, and, therefore, the virus represents the first member of a novel type, named RV-C54
AB - Causative agents for more than 30 percent of respiratory infections remain unidentified, suggesting that unknown respiratory pathogens might be involved. In this study, antibody capture VIDISCA-454 (virus discovery cDNA-AFLP combined with Roche 454 high-throughput sequencing) resulted in the discovery of a novel type of rhinovirus C (RV-C). The virus has an RNA genome of at least 7054 nt and carries the characteristics of rhinovirus C species. The gene encoding viral protein 1, which is used for typing, has only 81% nucleotide sequence identity with the closest known RV-C type, and, therefore, the virus represents the first member of a novel type, named RV-C54
U2 - https://doi.org/10.3390/v7010239
DO - https://doi.org/10.3390/v7010239
M3 - Article
C2 - 25606972
SN - 1999-4915
VL - 7
SP - 239
EP - 251
JO - Viruses
JF - Viruses
IS - 1
ER -