TY - JOUR
T1 - Identification of undiagnosed dementia cases using a web-based pre-screening tool: The MOPEAD project
AU - Rodrigo, Adrián
AU - Trigueros, Paloma
AU - Jamilis, Laura
AU - Alegret, Montserrat
AU - Rodríguez, Octavio
AU - Tárraga, Lluís
AU - González-Pérez, Antonio
AU - Kramberger, Milica
AU - Winblad, Bengt
AU - Visser, Pieter Jelle
AU - Jessen, Frank
AU - Campo, Laura
AU - Boada, Mercè
AU - the MOPEAD consortium
AU - Valero, Sergi
AU - Rodriguez, Isabel
AU - Gurruchaga, Miren
AU - Iradier, Fatima
AU - Belger, Mark
AU - Dumas, Annette
AU - Shering, Craig
AU - Maguire, Peggy
AU - Semancik, Kristin
AU - Pérez Garro, Inmaculada
AU - Johansson, Gunilla
AU - Wimo, Anders
AU - Zlobec, Stefania
AU - Krivec, David
AU - Sannemann, Lena
AU - Bon, Jaka
AU - Simo, Rafael
AU - Cuidin, Andreea
AU - Zwan, Marissa
AU - Vermunt, Lisa
AU - Stoekenbroek, Malou
AU - Waterink, Lisa
AU - Georges, Jean
N1 - Funding Information: This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under Grant Agreement No 115985. This Joint Undertaking receives support from the European Union's Horizon 2020 Research and Innovation program and the European Federation of Pharmaceutical Industries and Associations. www.imi.europa.eu/ . Publisher Copyright: © 2021 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/8
Y1 - 2021/8
N2 - Introduction: Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting. Methods: A marketing campaign and a web-based pre-screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project. Results: A total of 1487 individuals completed the pre-screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre-screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease. Conclusion: This novel web-based pre-screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.
AB - Introduction: Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting. Methods: A marketing campaign and a web-based pre-screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project. Results: A total of 1487 individuals completed the pre-screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre-screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease. Conclusion: This novel web-based pre-screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.
KW - Alzheimer's disease
KW - diagnostic gap
KW - early diagnosis
KW - patient engagement
KW - population-based screening
UR - http://www.scopus.com/inward/record.url?scp=85104766432&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/alz.12297
DO - https://doi.org/10.1002/alz.12297
M3 - Article
C2 - 33860599
SN - 1552-5260
VL - 17
SP - 1307
EP - 1316
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
IS - 8
ER -