TY - JOUR
T1 - ILCs in hematologic malignancies: Tumor cell killers and tissue healers
AU - Blom, Bianca
AU - van Hoeven, Vera
AU - Hazenberg, Mette D.
N1 - Copyright © 2019 The Author. Published by Elsevier Ltd.. All rights reserved.
PY - 2019/2
Y1 - 2019/2
N2 - Innate lymphoid cells (ILCs) have attracted considerable attention in the past years. As modulators of epithelial barrier immunology and homeostasis they play important roles in (auto)immunity and inflammation. Here we review the role of ILCs in hematologic malignancies, where ILCs act as efficient killer cells and as tissue healers, in the context of chemotherapy, radiotherapy and after allogeneic hematopoietic stem cell transplantation (HSCT).
AB - Innate lymphoid cells (ILCs) have attracted considerable attention in the past years. As modulators of epithelial barrier immunology and homeostasis they play important roles in (auto)immunity and inflammation. Here we review the role of ILCs in hematologic malignancies, where ILCs act as efficient killer cells and as tissue healers, in the context of chemotherapy, radiotherapy and after allogeneic hematopoietic stem cell transplantation (HSCT).
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85067016032&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/31200953
U2 - https://doi.org/10.1016/j.smim.2019.06.002
DO - https://doi.org/10.1016/j.smim.2019.06.002
M3 - Review article
C2 - 31200953
SN - 1044-5323
VL - 41
SP - 101279
JO - Seminars in Immunology
JF - Seminars in Immunology
ER -