Immunology and barrier function of the skin

Thomas Rustemeyer; Manigé Fartasch

doi:https://doi.org/10.1007/978-3-319-68617-2_1

Immunology and barrier function of the skin

Thomas Rustemeyer, Manigé Fartasch

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

1 Citation (Scopus)

Abstract

A disturbed epidermal barrier may lead to irritant contact dermatitis. An enhanced penetration through skin barrier may facilitate sensitization. Immunological effects induced by pre-irritation and barrier alteration may further lead to the induction of allergic Type IV-contact dermatitis and Type I (immediate-type reaction) reactions or aggravate allergic reactions.

Original language	English
Title of host publication	Kanerva's Occupational Dermatology
Publisher	Springer International Publishing AG
Pages	3-10
Number of pages	8
ISBN (Electronic)	9783319686172
ISBN (Print)	9783319686158
DOIs	https://doi.org/10.1007/978-3-319-68617-2_1
Publication status	Published - 1 Jan 2019

Keywords

Atopic eczema (AE)
Cornified cell envelope
Epidermal permeability barrier
Filaggrin
Keratohyalin
Netherton’s syndrome (NS)
Transepidermal water loss (TEWL)

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https://doi.org/10.1007/978-3-319-68617-2_1

Cite this

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KW - Keratohyalin

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ER -

Immunology and barrier function of the skin

Abstract

Keywords

Access to Document

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