Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity

Maaike E. Ressing; Rienk Offringa; René E.M. Toes; Ferry Ossendorp; Joan H. De Jong; Remco M.P. Brandt; W. Martin Kast; Cornelis J.M. Melief

doi:https://doi.org/10.1016/S1380-2933(96)00057-7

Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity

Maaike E. Ressing, Rienk Offringa, René E.M. Toes, Ferry Ossendorp, Joan H. De Jong, Remco M.P. Brandt, W. Martin Kast, Cornelis J.M. Melief

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

Abstract

Recent progress in defining the molecular nature of antigens and in finding ways to manipulate T cell-mediated immune responses may provide new modalities for cancer treatment. In this report, we review preclinical studies as well as the first clinical trials with vaccination strategies aiming at the induction of anti-tumor immunity. In particular, we focus on the development of a vaccine against human papillomavirus-induced cervical carcinoma.

Original language	English
Pages (from-to)	241-251
Number of pages	11
Journal	Immunotechnology
Volume	2
Issue number	4
DOIs	https://doi.org/10.1016/S1380-2933(96)00057-7
Publication status	Published - Nov 1996

Keywords

Cervical carcinoma
Lymphocytes
T cells

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https://doi.org/10.1016/S1380-2933(96)00057-7

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@article{27d8ca076f3444729766b12540611607,

title = "Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity",

abstract = "Recent progress in defining the molecular nature of antigens and in finding ways to manipulate T cell-mediated immune responses may provide new modalities for cancer treatment. In this report, we review preclinical studies as well as the first clinical trials with vaccination strategies aiming at the induction of anti-tumor immunity. In particular, we focus on the development of a vaccine against human papillomavirus-induced cervical carcinoma.",

keywords = "Cervical carcinoma, Lymphocytes, T cells",

author = "Ressing, {Maaike E.} and Rienk Offringa and Toes, {Ren{\'e} E.M.} and Ferry Ossendorp and {De Jong}, {Joan H.} and Brandt, {Remco M.P.} and Kast, {W. Martin} and Melief, {Cornelis J.M.}",

note = "Funding Information: In part, these studies were funded by the Dutch Cancer Foundation (grants RUL93-560, 93-588, 95-1089) and by the National Institute of Health of the USA (grant 1RO1-CA57933 to M.K.).",

year = "1996",

month = nov,

doi = "https://doi.org/10.1016/S1380-2933(96)00057-7",

language = "English",

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pages = "241--251",

journal = "Immunotechnology",

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T1 - Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity

AU - Ressing, Maaike E.

AU - Offringa, Rienk

AU - Toes, René E.M.

AU - Ossendorp, Ferry

AU - De Jong, Joan H.

AU - Brandt, Remco M.P.

AU - Kast, W. Martin

AU - Melief, Cornelis J.M.

N1 - Funding Information: In part, these studies were funded by the Dutch Cancer Foundation (grants RUL93-560, 93-588, 95-1089) and by the National Institute of Health of the USA (grant 1RO1-CA57933 to M.K.).

PY - 1996/11

Y1 - 1996/11

N2 - Recent progress in defining the molecular nature of antigens and in finding ways to manipulate T cell-mediated immune responses may provide new modalities for cancer treatment. In this report, we review preclinical studies as well as the first clinical trials with vaccination strategies aiming at the induction of anti-tumor immunity. In particular, we focus on the development of a vaccine against human papillomavirus-induced cervical carcinoma.

AB - Recent progress in defining the molecular nature of antigens and in finding ways to manipulate T cell-mediated immune responses may provide new modalities for cancer treatment. In this report, we review preclinical studies as well as the first clinical trials with vaccination strategies aiming at the induction of anti-tumor immunity. In particular, we focus on the development of a vaccine against human papillomavirus-induced cervical carcinoma.

KW - Cervical carcinoma

KW - Lymphocytes

KW - T cells

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M3 - Article

C2 - 9373306

SN - 1380-2933

VL - 2

SP - 241

EP - 251

JO - Immunotechnology

JF - Immunotechnology

IS - 4

ER -

Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity

Abstract

Keywords

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