TY - JOUR
T1 - Impact of assisted reproductive technology on the incidence of multiple-gestation infants: a population perspective
T2 - a population perspective
AU - Scholten, Irma
AU - Chambers, Georgina M.
AU - van Loendersloot, Laura
AU - van der Veen, Fulco
AU - Repping, Sjoerd
AU - Gianotten, Judith
AU - Hompes, Peter G. A.
AU - Ledger, William
AU - Mol, Ben W. J.
N1 - Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
PY - 2015/1
Y1 - 2015/1
N2 - To study the value of a population view in assessing assisted reproductive technology (ART) multiple-gestation infants. Descriptive comparison of ART treatment and population statistics in seven developed countries (United States [U.S.], South Korea, United Kingdom, the Netherlands, Australia, Belgium, Denmark) with varying ART utilization and single-embryo transfer (SET) rates. Not applicable. Not applicable. None. The contribution of ART multiple-gestation infants to the total number of multiple-gestation infants in a population was calculated in relation to utilization of ART and SET rates. The number of ART treatments leading to embryo transfer varied from 304 per million inhabitants in the U.S. to 1,518 in Denmark. The percentage of ART cycles that utilized SET varied from 8.8% in South Korea to 53.3% in Australia. Reflecting both utilization rates and SET rates, the percentage of multiple-gestation infants in the population attributed to ART ranged from 14.7% in South Korea to 29.0% in Denmark. In seven countries, the contribution of ART multiple-gestation infants to all multiple-gestation infants varies from 14.7% to 29.0%, a percentage that was influenced by both the SET rate per cycle and ART utilization rates. In the monitoring of safety and efficacy of fertility treatment, registration of the percentage of SET cycles alone might not be sufficient
AB - To study the value of a population view in assessing assisted reproductive technology (ART) multiple-gestation infants. Descriptive comparison of ART treatment and population statistics in seven developed countries (United States [U.S.], South Korea, United Kingdom, the Netherlands, Australia, Belgium, Denmark) with varying ART utilization and single-embryo transfer (SET) rates. Not applicable. Not applicable. None. The contribution of ART multiple-gestation infants to the total number of multiple-gestation infants in a population was calculated in relation to utilization of ART and SET rates. The number of ART treatments leading to embryo transfer varied from 304 per million inhabitants in the U.S. to 1,518 in Denmark. The percentage of ART cycles that utilized SET varied from 8.8% in South Korea to 53.3% in Australia. Reflecting both utilization rates and SET rates, the percentage of multiple-gestation infants in the population attributed to ART ranged from 14.7% in South Korea to 29.0% in Denmark. In seven countries, the contribution of ART multiple-gestation infants to all multiple-gestation infants varies from 14.7% to 29.0%, a percentage that was influenced by both the SET rate per cycle and ART utilization rates. In the monitoring of safety and efficacy of fertility treatment, registration of the percentage of SET cycles alone might not be sufficient
KW - Adolescent
KW - Europe/epidemiology
KW - Female
KW - Fertilization in Vitro/statistics & numerical data
KW - Humans
KW - Incidence
KW - Population Dynamics
KW - Pregnancy
KW - Pregnancy Outcome/epidemiology
KW - Pregnancy, Multiple/statistics & numerical data
KW - Republic of Korea/epidemiology
KW - Single Embryo Transfer/statistics & numerical data
KW - Sperm Injections, Intracytoplasmic/statistics & numerical data
KW - United States/epidemiology
U2 - https://doi.org/10.1016/j.fertnstert.2014.09.033
DO - https://doi.org/10.1016/j.fertnstert.2014.09.033
M3 - Article
C2 - 25439839
SN - 0015-0282
VL - 103
SP - 179
EP - 183
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 1
ER -