Impaired Hyperemic Myocardial Blood Flow Is Associated With Inducibility of Ventricular Arrhythmia in Ischemic Cardiomyopathy

M.T. Rijnierse; S. de Haan; H.J. Harms; L.F. Robbers; L.N. Wu; I. Danad; A.M. Beek; M.W. Heymans; A.C. van Rossum; A.A. Lammertsma; C.P. Allaart; P. Knaapen

doi:https://doi.org/10.1161/CIRCIMAGING.113.001158

Impaired Hyperemic Myocardial Blood Flow Is Associated With Inducibility of Ventricular Arrhythmia in Ischemic Cardiomyopathy

M.T. Rijnierse, S. de Haan, H.J. Harms, L.F. Robbers, L.N. Wu, I. Danad, A.M. Beek, M.W. Heymans, A.C. van Rossum, A.A. Lammertsma, C.P. Allaart, P. Knaapen

Research output: Contribution to journal › Article › Academic › peer-review

23 Citations (Scopus)

Abstract

Background-Risk stratification for ventricular arrhythmias (VAs) is important to refine selection criteria for primary prevention implantable cardioverter defibrillator therapy. Impaired hyperemic myocardial blood flow (MBF) is associated with increased mortality rate in ischemic and nonischemic cardiomyopathy, which may be attributed to electric instability inducing VAs. The aim of this pilot study was to assess whether hyperemic MBF impairment may be related with VA inducibility in patients with ischemic cardiomyopathy. Methods and Results-Thirty patients with ischemic cardiomyopathy referred for primary prevention implantable cardioverter defibrillator implantation were prospectively included (26 men; 65±8 years old; left ventricular ejection fraction, 29±6%). [

Original language	English
Pages (from-to)	20-30
Journal	Circulation.Cardiovascular Imaging
Volume	7
Issue number	1
DOIs	https://doi.org/10.1161/CIRCIMAGING.113.001158
Publication status	Published - 2014

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Cite this

Rijnierse, M. T., de Haan, S., Harms, H. J., Robbers, L. F., Wu, L. N., Danad, I., Beek, A. M., Heymans, M. W., van Rossum, A. C., Lammertsma, A. A., Allaart, C. P., & Knaapen, P. (2014). Impaired Hyperemic Myocardial Blood Flow Is Associated With Inducibility of Ventricular Arrhythmia in Ischemic Cardiomyopathy. Circulation.Cardiovascular Imaging, 7(1), 20-30. https://doi.org/10.1161/CIRCIMAGING.113.001158

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abstract = "Background-Risk stratification for ventricular arrhythmias (VAs) is important to refine selection criteria for primary prevention implantable cardioverter defibrillator therapy. Impaired hyperemic myocardial blood flow (MBF) is associated with increased mortality rate in ischemic and nonischemic cardiomyopathy, which may be attributed to electric instability inducing VAs. The aim of this pilot study was to assess whether hyperemic MBF impairment may be related with VA inducibility in patients with ischemic cardiomyopathy. Methods and Results-Thirty patients with ischemic cardiomyopathy referred for primary prevention implantable cardioverter defibrillator implantation were prospectively included (26 men; 65±8 years old; left ventricular ejection fraction, 29±6%). [",

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Rijnierse, MT, de Haan, S, Harms, HJ, Robbers, LF, Wu, LN, Danad, I, Beek, AM, Heymans, MW , van Rossum, AC , Lammertsma, AA , Allaart, CP & Knaapen, P 2014, 'Impaired Hyperemic Myocardial Blood Flow Is Associated With Inducibility of Ventricular Arrhythmia in Ischemic Cardiomyopathy', Circulation.Cardiovascular Imaging, vol. 7, no. 1, pp. 20-30. https://doi.org/10.1161/CIRCIMAGING.113.001158

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AU - Rijnierse, M.T.

AU - de Haan, S.

AU - Harms, H.J.

AU - Robbers, L.F.

AU - Wu, L.N.

AU - Danad, I.

AU - Beek, A.M.

AU - Heymans, M.W.

AU - van Rossum, A.C.

AU - Lammertsma, A.A.

AU - Allaart, C.P.

AU - Knaapen, P.

PY - 2014

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AB - Background-Risk stratification for ventricular arrhythmias (VAs) is important to refine selection criteria for primary prevention implantable cardioverter defibrillator therapy. Impaired hyperemic myocardial blood flow (MBF) is associated with increased mortality rate in ischemic and nonischemic cardiomyopathy, which may be attributed to electric instability inducing VAs. The aim of this pilot study was to assess whether hyperemic MBF impairment may be related with VA inducibility in patients with ischemic cardiomyopathy. Methods and Results-Thirty patients with ischemic cardiomyopathy referred for primary prevention implantable cardioverter defibrillator implantation were prospectively included (26 men; 65±8 years old; left ventricular ejection fraction, 29±6%). [

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