Impaired Hyperemic Myocardial Blood Flow Is Associated With Inducibility of Ventricular Arrhythmia in Ischemic Cardiomyopathy

M.T. Rijnierse, S. de Haan, H.J. Harms, L.F. Robbers, L.N. Wu, I. Danad, A.M. Beek, M.W. Heymans, A.C. van Rossum, A.A. Lammertsma, C.P. Allaart, P. Knaapen

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Background-Risk stratification for ventricular arrhythmias (VAs) is important to refine selection criteria for primary prevention implantable cardioverter defibrillator therapy. Impaired hyperemic myocardial blood flow (MBF) is associated with increased mortality rate in ischemic and nonischemic cardiomyopathy, which may be attributed to electric instability inducing VAs. The aim of this pilot study was to assess whether hyperemic MBF impairment may be related with VA inducibility in patients with ischemic cardiomyopathy. Methods and Results-Thirty patients with ischemic cardiomyopathy referred for primary prevention implantable cardioverter defibrillator implantation were prospectively included (26 men; 65±8 years old; left ventricular ejection fraction, 29±6%). [
Original languageEnglish
Pages (from-to)20-30
JournalCirculation.Cardiovascular Imaging
Issue number1
Publication statusPublished - 2014

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