TY - JOUR
T1 - Improvement of developmental outcome between 24 and 36 months corrected age in very preterm infants
AU - Houtzager, Bregje A.
AU - Gorter-Overdiek, Bianca
AU - van Sonderen, Loekie
AU - Tamminga, Pieter
AU - van Wassenaer, Aleid G.
PY - 2010
Y1 - 2010
N2 - Aim: To study early developmental course in preschool-aged very preterm infants and its association with perinatal risk factors and test-taking behaviour. Methods: Children born <30 weeks gestation and/or <1000 g in the Academic Medical Center of Amsterdam were assessed at 24 and 36 months corrected age with the Dutch Bayley Scales of Infant Development-II (BSID-II-NL) and neurological examination. Linear regression analyses for developmental change were performed with perinatal risk factors. Results: One hundred and forty-six children, mean GA 28 weeks and mean birth weight 1043 g, participated. Mental and psychomotor scores improved significantly with 6 and 7 points, respectively, from 24 to 36 months (p <0.01). Mild to severe problems on at least one domain occurred less often at 36 (32%) compared to 24 months (63%) (p <0.01), using corrected scores. Mental improvement was associated with being born very small for gestational age or <28 weeks; psychomotor improvement was associated with not being treated with indomethacin. Difficult test behaviour occurred mostly at 24 months and was associated with non-optimal development at 36 months. Conclusion: Improved developmental outcome and test behaviour were found at 36 compared to 24 months in a cohort of very preterm children. Long-term outcome studies and retesting of behaviourally difficult children are recommended
AB - Aim: To study early developmental course in preschool-aged very preterm infants and its association with perinatal risk factors and test-taking behaviour. Methods: Children born <30 weeks gestation and/or <1000 g in the Academic Medical Center of Amsterdam were assessed at 24 and 36 months corrected age with the Dutch Bayley Scales of Infant Development-II (BSID-II-NL) and neurological examination. Linear regression analyses for developmental change were performed with perinatal risk factors. Results: One hundred and forty-six children, mean GA 28 weeks and mean birth weight 1043 g, participated. Mental and psychomotor scores improved significantly with 6 and 7 points, respectively, from 24 to 36 months (p <0.01). Mild to severe problems on at least one domain occurred less often at 36 (32%) compared to 24 months (63%) (p <0.01), using corrected scores. Mental improvement was associated with being born very small for gestational age or <28 weeks; psychomotor improvement was associated with not being treated with indomethacin. Difficult test behaviour occurred mostly at 24 months and was associated with non-optimal development at 36 months. Conclusion: Improved developmental outcome and test behaviour were found at 36 compared to 24 months in a cohort of very preterm children. Long-term outcome studies and retesting of behaviourally difficult children are recommended
U2 - https://doi.org/10.1111/j.1651-2227.2010.01953.x
DO - https://doi.org/10.1111/j.1651-2227.2010.01953.x
M3 - Article
C2 - 20670310
SN - 0803-5253
VL - 99
SP - 1801
EP - 1806
JO - Acta paediatrica (Oslo, Norway
JF - Acta paediatrica (Oslo, Norway
IS - 12
ER -