In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M Schluep; H Endeman; B Y Gravesteijn; C Kuijs; M J Blans; B van den Bogaard; A W M M Koopman Van Gemert; C J Hukshorn; B J M van der Meer; A H M Knook; T van Melsen; R Peters; K S Simons; G Spijkers; J W Vermeijden; E-J Wils; R J Stolker; S E Hoeks

doi:https://doi.org/10.1016/j.jcrc.2021.11.008

In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M Schluep, H Endeman, B Y Gravesteijn, C Kuijs, M J Blans, B van den Bogaard, A W M M Koopman Van Gemert, C J Hukshorn, B J M van der Meer, A H M Knook, T van Melsen, R Peters, K S Simons, G Spijkers, J W Vermeijden, E-J Wils, R J Stolker, S E Hoeks

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

INTRODUCTION: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA.

METHODS: A multicenter prospective cohort study in 25 hospitals between January 2017 - May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA.

RESULTS: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65-0.87) at 3 months and 0.81 (0.70-0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8-46.5) and mental component scale (MCS) of 43.5 (34.0-39.7) and at 12 months a PCS of 43.1 (34.6-52.3) and MCS 46.9 (38.5-54.5).

DISCUSSION: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

Original language	English
Pages (from-to)	22-30
Number of pages	9
Journal	Journal of Critical Care
Volume	68
DOIs	https://doi.org/10.1016/j.jcrc.2021.11.008
Publication status	Published - Apr 2022

Keywords

Adult
Heart Arrest
Hospitals
Humans
Male
Prospective Studies
Quality of Life
Surveys and Questionnaires
Survivors/psychology

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https://doi.org/10.1016/j.jcrc.2021.11.008

Cite this

Schluep, M., Endeman, H., Gravesteijn, B. Y., Kuijs, C., Blans, M. J., van den Bogaard, B., Van Gemert, A. W. M. M. K., Hukshorn, C. J., van der Meer, B. J. M., Knook, A. H. M., van Melsen, T., Peters, R., Simons, K. S., Spijkers, G., Vermeijden, J. W., Wils, E.-J., Stolker, R. J., & Hoeks, S. E. (2022). In-depth assessment of health-related quality of life after in-hospital cardiac arrest. Journal of Critical Care, 68, 22-30. https://doi.org/10.1016/j.jcrc.2021.11.008

@article{77eed912e4be45c4ba78f315b11e60df,

title = "In-depth assessment of health-related quality of life after in-hospital cardiac arrest",

abstract = "INTRODUCTION: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA.METHODS: A multicenter prospective cohort study in 25 hospitals between January 2017 - May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA.RESULTS: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65-0.87) at 3 months and 0.81 (0.70-0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8-46.5) and mental component scale (MCS) of 43.5 (34.0-39.7) and at 12 months a PCS of 43.1 (34.6-52.3) and MCS 46.9 (38.5-54.5).DISCUSSION: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.",

keywords = "Adult, Heart Arrest, Hospitals, Humans, Male, Prospective Studies, Quality of Life, Surveys and Questionnaires, Survivors/psychology",

author = "M Schluep and H Endeman and Gravesteijn, {B Y} and C Kuijs and Blans, {M J} and {van den Bogaard}, B and {Van Gemert}, {A W M M Koopman} and Hukshorn, {C J} and {van der Meer}, {B J M} and Knook, {A H M} and {van Melsen}, T and R Peters and Simons, {K S} and G Spijkers and Vermeijden, {J W} and E-J Wils and Stolker, {R J} and Hoeks, {S E}",

year = "2022",

month = apr,

doi = "https://doi.org/10.1016/j.jcrc.2021.11.008",

language = "English",

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Schluep, M, Endeman, H, Gravesteijn, BY, Kuijs, C, Blans, MJ, van den Bogaard, B, Van Gemert, AWMMK, Hukshorn, CJ, van der Meer, BJM, Knook, AHM, van Melsen, T, Peters, R, Simons, KS, Spijkers, G, Vermeijden, JW, Wils, E-J, Stolker, RJ & Hoeks, SE 2022, 'In-depth assessment of health-related quality of life after in-hospital cardiac arrest', Journal of Critical Care, vol. 68, pp. 22-30. https://doi.org/10.1016/j.jcrc.2021.11.008

TY - JOUR

T1 - In-depth assessment of health-related quality of life after in-hospital cardiac arrest

AU - Schluep, M

AU - Endeman, H

AU - Gravesteijn, B Y

AU - Kuijs, C

AU - Blans, M J

AU - van den Bogaard, B

AU - Van Gemert, A W M M Koopman

AU - Hukshorn, C J

AU - van der Meer, B J M

AU - Knook, A H M

AU - van Melsen, T

AU - Peters, R

AU - Simons, K S

AU - Spijkers, G

AU - Vermeijden, J W

AU - Wils, E-J

AU - Stolker, R J

AU - Hoeks, S E

PY - 2022/4

Y1 - 2022/4

N2 - INTRODUCTION: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA.METHODS: A multicenter prospective cohort study in 25 hospitals between January 2017 - May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA.RESULTS: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65-0.87) at 3 months and 0.81 (0.70-0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8-46.5) and mental component scale (MCS) of 43.5 (34.0-39.7) and at 12 months a PCS of 43.1 (34.6-52.3) and MCS 46.9 (38.5-54.5).DISCUSSION: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

AB - INTRODUCTION: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA.METHODS: A multicenter prospective cohort study in 25 hospitals between January 2017 - May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA.RESULTS: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65-0.87) at 3 months and 0.81 (0.70-0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8-46.5) and mental component scale (MCS) of 43.5 (34.0-39.7) and at 12 months a PCS of 43.1 (34.6-52.3) and MCS 46.9 (38.5-54.5).DISCUSSION: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

KW - Adult

KW - Heart Arrest

KW - Hospitals

KW - Humans

KW - Male

KW - Prospective Studies

KW - Quality of Life

KW - Surveys and Questionnaires

KW - Survivors/psychology

U2 - https://doi.org/10.1016/j.jcrc.2021.11.008

DO - https://doi.org/10.1016/j.jcrc.2021.11.008

M3 - Article

C2 - 34856490

SN - 0883-9441

VL - 68

SP - 22

EP - 30

JO - Journal of Critical Care

JF - Journal of Critical Care

ER -