In vivo endoscopic multifunctional optical coherence tomography imaging of lungs periphery before and after bronchial thermoplasty

Margherita Vaselli, Fabio Feroldi, Joy Willemse, Maximilian G.O. Graefe, Dirck van Iperen, Annika W.M. Goorsenberg, Peter I. Bonta, Jouke T. Annema, Johannes F. de Boer

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    We demonstrate the use of a motorized distal scanning endoscope to acquire in vivo data in lungs of severe-asthma patients before and after an asthma treatment procedure called bronchial thermoplasty. Conventional optical coherence tomography (OCT) intensity images and polarisation sensitive OCT images were extracted from the acquired data. PS-OCT endoscopy allowing the visualization and segmentation of airway smooth muscle layer - which plays a key role in bronchoconstriction during asthma attacks - showed its potential as means to evaluate the effectiveness of bronchial thermoplasty.
    Original languageEnglish
    Article number04002
    Pages (from-to)1-2
    Number of pages2
    JournalEPJ Web of Conferences
    Volume238
    Early online date20 Aug 2020
    DOIs
    Publication statusPublished - 2020

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