TY - JOUR
T1 - Increased risk of respiratory tract infections in children with Down syndrome: the consequence of an altered immune system
AU - Bloemers, Beatrijs L. P.
AU - Broers, Chantal J. M.
AU - Bont, Louis
AU - Weijerman, Michel E.
AU - Gemke, Reinoud J. B. J.
AU - van Furth, A. Marceline
PY - 2010
Y1 - 2010
N2 - Down syndrome (DS) is the most common chromosomal abnormality among live-born infants. Respiratory tract infections are the most important cause of mortality in individuals with DS at all ages. In recent decades several studies have been performed to elucidate abnormalities of the immune system in DS. However, the influence of the immune system on the occurrence of respiratory tract infections in these children has never been reviewed
AB - Down syndrome (DS) is the most common chromosomal abnormality among live-born infants. Respiratory tract infections are the most important cause of mortality in individuals with DS at all ages. In recent decades several studies have been performed to elucidate abnormalities of the immune system in DS. However, the influence of the immune system on the occurrence of respiratory tract infections in these children has never been reviewed
U2 - https://doi.org/10.1016/j.micinf.2010.05.007
DO - https://doi.org/10.1016/j.micinf.2010.05.007
M3 - Review article
C2 - 20685340
SN - 1286-4579
VL - 12
SP - 799
EP - 808
JO - Microbes and infection / Institut Pasteur
JF - Microbes and infection / Institut Pasteur
IS - 11
ER -