Indications for an early invasive strategy in NSTE-ACS patients

B. Zwart, J. M. ten Berg, A. W. van ’t Hof, P. A. L. Tonino, Y. Appelman, A. H. Liem, F. Arslan, J. Waltenberger, J. W. Jukema, R. J. de Winter, P. Damman

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5 Citations (Scopus)


An early invasive strategy in patients who have acute coronary syndrome without ST-elevation (NSTE-ACS) can improve clinical outcome in high-risk subgroups. According to the current guidelines of the European Society of Cardiology (ESC), the majority of NSTE-ACS patients are classified as “high-risk”. We propose to prioritise patients with a global registry of acute coronary events (GRACE) risk score >140 over patients with isolated troponin rise or electrocardiographic changes and a GRACE risk score <140. We also acknowledge that same-day transfer for all patients at a high risk is not necessary in the Netherlands since the majority of Dutch cardiology departments are equipped with a catheterisation laboratory where diagnostic coronary angiography is routinely performed in NSTE-ACS patients. Therefore, same-day transfer should be restricted to true high-risk patients (in addition to those NSTE-ACS patients with very high-risk (VHR) criteria) in centres without coronary angiography capabilities.
Original languageEnglish
Pages (from-to)131-135
Number of pages5
JournalNetherlands heart journal
Issue number3
Early online date6 Nov 2019
Publication statusPublished - 1 Mar 2020


  • Acute coronary syndrome
  • Coronary angiography
  • Timing

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