TY - JOUR
T1 - Influence of a positive family history and associated allergic diseases on the natural course of asthma
AU - Roorda, R. J.
AU - Gerritsen, J.
AU - van Aalderen, W. M.
AU - Knol, K.
PY - 1992
Y1 - 1992
N2 - The outcome of childhood asthma was studied in a cohort of 406 asthmatic children, with emphasis on the influence of family history for allergic disease, as well as the influence of associated allergic diseases on prognosis. Sixty-two per cent had a positive family history for atopy. In young adulthood no differences, either in symptoms or lung function were demonstrated in comparison to subjects with a negative family history. Fifty-two per cent of the children had no other allergic disease, 48% had either eczema or hay fever or both. When subjects were stratified based on associated allergic disease, no differences in outcome in adulthood were revealed either. It is concluded that neither a positive family history, nor concurrent associated allergic diseases in the child contribute to the prognosis of asthma from childhood to young adulthood. Therefore, environmental factors as well as patient characteristics (including lung function level, level of bronchial responsiveness) are likely to be more important for the prognosis
AB - The outcome of childhood asthma was studied in a cohort of 406 asthmatic children, with emphasis on the influence of family history for allergic disease, as well as the influence of associated allergic diseases on prognosis. Sixty-two per cent had a positive family history for atopy. In young adulthood no differences, either in symptoms or lung function were demonstrated in comparison to subjects with a negative family history. Fifty-two per cent of the children had no other allergic disease, 48% had either eczema or hay fever or both. When subjects were stratified based on associated allergic disease, no differences in outcome in adulthood were revealed either. It is concluded that neither a positive family history, nor concurrent associated allergic diseases in the child contribute to the prognosis of asthma from childhood to young adulthood. Therefore, environmental factors as well as patient characteristics (including lung function level, level of bronchial responsiveness) are likely to be more important for the prognosis
U2 - https://doi.org/10.1111/j.1365-2222.1992.tb00179.x
DO - https://doi.org/10.1111/j.1365-2222.1992.tb00179.x
M3 - Article
C2 - 1393760
SN - 0954-7894
VL - 22
SP - 627
EP - 634
JO - Clinical and experimental allergy
JF - Clinical and experimental allergy
IS - 6
ER -