Abstract
Activation of μ receptors by DAGO resulted in inhibition of cortical noradrenaline release and striatal dopamine-sensitive adenylate cyclase (AC) activity as early as gestational day 17 (E17). The κ agonist U50,488 had already inhibited striatal dopamine release on E17. In contrast, functional δ receptors emerged postnatally, mediating inhibition of striatal acetylcholine release on postnatal day 7 (P7) and of AC activity on P14.
Original language | English |
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Title of host publication | New leads in opioid research |
Subtitle of host publication | proceedings of the International Narcotics Research Conference. ICS914 |
Editors | J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus |
Publisher | Elsevier Science Publishers B.V. |
Number of pages | 1 |
ISBN (Print) | 044481213X |
Publication status | Published - 1 Jan 1990 |
Event | The International Narcotics Research Conference - Duration: 8 Jul 1989 → 13 Jul 1989 |
Conference
Conference | The International Narcotics Research Conference |
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Period | 8/07/1989 → 13/07/1989 |