Abstract
An allergic reaction develops in 2.4% of patients that use insulin. This ranges in severity from erythema and pruritus to life-threatening anaphylaxis. Allergic reactions to insulin usually occur within a few hours after an injection and are usually due to a local or systemic type I IgE-mediated hypersensitivity reaction. Despite considerable research into the immunogenicity of insulin, this has not yet been clarified completely and allergic reactions to insulin still occur. A systematic diagnostic approach is essential for an adequate treatment plan. A blood test for anti-insulin antibodies and intradermal skin tests are of great importance. There are many options available for the treatment of insulin allergy and each patient must therefore be evaluated individually.
| Translated title of the contribution | Insulin allergy: Background, diagnostics and treatment |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 2783-2788 |
| Number of pages | 6 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 149 |
| Issue number | 50 |
| Publication status | Published - 10 Dec 2005 |