TY - JOUR
T1 - International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR): Study protocol and statistical analysis plan
AU - on behalf of the AVATaR and PROVE Network investigators
AU - Queiroz, Veronica Neves Fialho
AU - da Costa, Luiz Guilherme Villares
AU - Barbosa, Rogerio P. voa
AU - Takaoka, Flávio
AU - de Baerdemaeker, Luc
AU - Cesar, Daniel Souza
AU - D'Orto, Ulisses Cardoso
AU - Galdi, José Roberto
AU - Gottumukkala, Vijaya
AU - Cata, Juan P.
AU - Hemmes, Sabrine N. T.
AU - Hollman, Markus W.
AU - Kalmar, Alain
AU - de Moura, Lucas A. B.
AU - Mariano, Renato M.
AU - Matot, Idit
AU - Mazzinari, Guido
AU - Mills, Gary H.
AU - Posso, Irimar De Paula
AU - Teruya, Alexandre
AU - Vidal Melo, Marcos Francisco
AU - Sprung, Juraj
AU - Weingarten, Toby N.
AU - Treschan, Tanja A.
AU - Koopman, Seppe
AU - Eidelman, Leonid
AU - Chen, Lee-Lynn
AU - Lee, Jae-Woo
AU - Ariño Irujo, Jose J.
AU - Tena, Beatriz
AU - Groeben, Harald
AU - Pelosi, Paolo
AU - de Abreu, Marcelo Gama
AU - Schultz, Marcus J.
AU - Neto, Ary Serpa
AU - Catala, Juan
AU - Bravo, Mauro
AU - de Freitas, Renato Carneir
AU - Felipe, Chaves
AU - Bruno, Rothman
AU - Arantes, Schuind
AU - Hatanaka, Dina Mie
AU - Beltran, Joan
AU - Monsalve, Concepción
AU - Droger, Sijgje Mari
AU - Deljou, Atousa
AU - Sabov, Moldovan
AU - Rabbu, Yosef Sale
AU - del Barrio de Bonis, Marina
AU - Babian, Renate
PY - 2018
Y1 - 2018
N2 - Introduction Robotic-assisted surgery (RAS) has emerged as an alternative minimally invasive surgical option. Despite its growing applicability, the frequent need for pneumoperitoneum and Trendelenburg position could significantly affect respiratory mechanics during RAS. AVATaR is an international multicenter observational study aiming to assess the incidence of postoperative pulmonary complications (PPC), to characterise current practices of mechanical ventilation (MV) and to evaluate a possible association between ventilatory parameters and PPC in patients undergoing RAS. Methods and analysis AVATaR is an observational study of surgical patients undergoing MV for general anaesthesia for RAS. The primary outcome is the incidence of PPC during the first five postoperative days. Secondary outcomes include practice of MV, effect of surgical positioning on MV, effect of MV on clinical outcome and intraoperative complications. Ethics and dissemination This study was approved by the Institutional Review Board of the Hospital Israelita Albert Einstein. The study results will be published in peer-reviewed journals and disseminated at international conferences. Trial registration number NCT02989415; Pre-results.
AB - Introduction Robotic-assisted surgery (RAS) has emerged as an alternative minimally invasive surgical option. Despite its growing applicability, the frequent need for pneumoperitoneum and Trendelenburg position could significantly affect respiratory mechanics during RAS. AVATaR is an international multicenter observational study aiming to assess the incidence of postoperative pulmonary complications (PPC), to characterise current practices of mechanical ventilation (MV) and to evaluate a possible association between ventilatory parameters and PPC in patients undergoing RAS. Methods and analysis AVATaR is an observational study of surgical patients undergoing MV for general anaesthesia for RAS. The primary outcome is the incidence of PPC during the first five postoperative days. Secondary outcomes include practice of MV, effect of surgical positioning on MV, effect of MV on clinical outcome and intraoperative complications. Ethics and dissemination This study was approved by the Institutional Review Board of the Hospital Israelita Albert Einstein. The study results will be published in peer-reviewed journals and disseminated at international conferences. Trial registration number NCT02989415; Pre-results.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85053010335&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30139899
U2 - https://doi.org/10.1136/bmjopen-2018-021643
DO - https://doi.org/10.1136/bmjopen-2018-021643
M3 - Article
C2 - 30139899
SN - 2044-6055
VL - 8
JO - BMJ Open
JF - BMJ Open
IS - 8
M1 - e021643
ER -