TY - JOUR
T1 - Internet-based self-management plus education compared with usual care in asthma: a randomized trial
AU - van der Meer, Victor
AU - Bakker, Moira J.
AU - van den Hout, Wilbert B.
AU - Rabe, Klaus F.
AU - Sterk, Peter J.
AU - Kievit, Job
AU - Assendelft, Willem J. J.
AU - Sont, Jacob K.
AU - AUTHOR GROUP
AU - Assendelft, W. J. J.
AU - Thiadens, H. A.
AU - Bakker, M. J.
AU - van den Hout, W. B.
AU - Kievit, J.
AU - van der Meer, V.
AU - Sont, J. K.
AU - Kaptein, A. A.
AU - Rikkers-Mutsaerts, E. R. V. M.
AU - Rabe, K. F.
AU - Bel, E. H. D.
AU - Detmar, S. B.
AU - Otten, W.
AU - van Stel, H. F.
AU - Roldaan, A. C.
AU - de Jongste, J. C.
AU - Toussaint, P. J.
PY - 2009
Y1 - 2009
N2 - BACKGROUND: The Internet may support patient self-management of chronic conditions, such as asthma. OBJECTIVE: To evaluate the effectiveness of Internet-based asthma self-management. DESIGN: Randomized, controlled trial. SETTING: 37 general practices and 1 academic outpatient department in the Netherlands. PATIENTS: 200 adults with asthma who were treated with inhaled corticosteroids for 3 months or more during the previous year and had access to the Internet. MEASUREMENTS: Asthma-related quality of life at 12 months (minimal clinically significant difference of 0.5 on the 7-point scale), asthma control, symptom-free days, lung function, and exacerbations. INTERVENTION: Participants were randomly assigned by using a computer-generated permuted block scheme to Internet-based self-management (n = 101) or usual care (n = 99). The Internet-based self-management program included weekly asthma control monitoring and treatment advice, online and group education, and remote Web communications. RESULTS: Asthma-related quality of life improved by 0.56 and 0.18 points in the Internet and usual care groups, respectively (adjusted between-group difference, 0.38 [95% CI, 0.20 to 0.56]). An improvement of 0.5 point or more occurred in 54% and 27% of Internet and usual care patients, respectively (adjusted relative risk, 2.00 [CI, 1.38 to 3.04]). Asthma control improved more in the Internet group than in the usual care group (adjusted difference, -0.47 [CI, -0.64 to -0.30]). At 12 months, 63% of Internet patients and 52% of usual care patients reported symptom-free days in the previous 2 weeks (adjusted absolute difference, 10.9% [CI, 0.05% to 21.3%]). Prebronchodilator FEV1 changed with 0.24 L and -0.01 L for Internet and usual care patients, respectively (adjusted difference, 0.25 L [CI, 0.03 to 0.46 L]). Exacerbations did not differ between groups. LIMITATION: The study was unblinded and lasted only 12 months. CONCLUSION: Internet-based self-management resulted in improvements in asthma control and lung function but did not reduce exacerbations, and improvement in asthma-related quality of life was slightly less than clinically significant. PRIMARY FUNDING SOURCE: Netherlands Organization for Health Research and Development, ZonMw, and Netherlands Asthma Foundation
AB - BACKGROUND: The Internet may support patient self-management of chronic conditions, such as asthma. OBJECTIVE: To evaluate the effectiveness of Internet-based asthma self-management. DESIGN: Randomized, controlled trial. SETTING: 37 general practices and 1 academic outpatient department in the Netherlands. PATIENTS: 200 adults with asthma who were treated with inhaled corticosteroids for 3 months or more during the previous year and had access to the Internet. MEASUREMENTS: Asthma-related quality of life at 12 months (minimal clinically significant difference of 0.5 on the 7-point scale), asthma control, symptom-free days, lung function, and exacerbations. INTERVENTION: Participants were randomly assigned by using a computer-generated permuted block scheme to Internet-based self-management (n = 101) or usual care (n = 99). The Internet-based self-management program included weekly asthma control monitoring and treatment advice, online and group education, and remote Web communications. RESULTS: Asthma-related quality of life improved by 0.56 and 0.18 points in the Internet and usual care groups, respectively (adjusted between-group difference, 0.38 [95% CI, 0.20 to 0.56]). An improvement of 0.5 point or more occurred in 54% and 27% of Internet and usual care patients, respectively (adjusted relative risk, 2.00 [CI, 1.38 to 3.04]). Asthma control improved more in the Internet group than in the usual care group (adjusted difference, -0.47 [CI, -0.64 to -0.30]). At 12 months, 63% of Internet patients and 52% of usual care patients reported symptom-free days in the previous 2 weeks (adjusted absolute difference, 10.9% [CI, 0.05% to 21.3%]). Prebronchodilator FEV1 changed with 0.24 L and -0.01 L for Internet and usual care patients, respectively (adjusted difference, 0.25 L [CI, 0.03 to 0.46 L]). Exacerbations did not differ between groups. LIMITATION: The study was unblinded and lasted only 12 months. CONCLUSION: Internet-based self-management resulted in improvements in asthma control and lung function but did not reduce exacerbations, and improvement in asthma-related quality of life was slightly less than clinically significant. PRIMARY FUNDING SOURCE: Netherlands Organization for Health Research and Development, ZonMw, and Netherlands Asthma Foundation
M3 - Article
C2 - 19620163
SN - 0003-4819
VL - 151
SP - 110
EP - 120
JO - Annals of Internal Medicine
JF - Annals of Internal Medicine
IS - 2
ER -