TY - JOUR
T1 - Interplay between Static and Dynamic Energy Transfer in Biofunctional Upconversion Nanoplatforms
AU - Ding, Y.
AU - Wu, F.
AU - Zhang, Y.
AU - Liu, X.
AU - de Jong, E.M.L.D.
AU - Gregorkiewicz, T.
AU - Hong, X.
AU - Liu, Y.
AU - Aalders, M.C.G.
AU - Buma, W.J.
AU - Zhang, H.
N1 - With supporting information
PY - 2015
Y1 - 2015
N2 - Clarification of the energy-transfer (ET) mechanism is of vital importance for constructing efficient upconversion nanoplatforms for biological/biomedical applications. Yet, most strategies of optimizing these nanoplatforms were casually based on a dynamic ET assumption. In this work, we have modeled quantitatively the shell-thickness-dependent interplay between dynamic and static ET in nanosystems and validated the model in a typical biofunctional upconversion nanoplatform composed of NaYF4:Er, Yb/NaYF4 upconversion nanoparticles (UCNPs), and energy-acceptor photosensitizing molecule Rose Bengal (RB). It was determined that with a proper thickness shell, the energy transferred via dynamic ET as well as static ET in this case could be significantly improved by similar to 4 and similar to 9 fold, respectively, compared with the total energy transferred from bare core UCNPs. Our results shall form the bedrock in designing highly efficient ET-based biofunctional nanoplatforms.
AB - Clarification of the energy-transfer (ET) mechanism is of vital importance for constructing efficient upconversion nanoplatforms for biological/biomedical applications. Yet, most strategies of optimizing these nanoplatforms were casually based on a dynamic ET assumption. In this work, we have modeled quantitatively the shell-thickness-dependent interplay between dynamic and static ET in nanosystems and validated the model in a typical biofunctional upconversion nanoplatform composed of NaYF4:Er, Yb/NaYF4 upconversion nanoparticles (UCNPs), and energy-acceptor photosensitizing molecule Rose Bengal (RB). It was determined that with a proper thickness shell, the energy transferred via dynamic ET as well as static ET in this case could be significantly improved by similar to 4 and similar to 9 fold, respectively, compared with the total energy transferred from bare core UCNPs. Our results shall form the bedrock in designing highly efficient ET-based biofunctional nanoplatforms.
UR - https://pure.uva.nl/ws/files/2591438/168857_Interplay_between_Static_and_Dynamic_Energy_Transfer_suppl.pdf
U2 - https://doi.org/10.1021/acs.jpclett.5b00999
DO - https://doi.org/10.1021/acs.jpclett.5b00999
M3 - Article
C2 - 26266728
SN - 1948-7185
VL - 6
SP - 2518
EP - 2523
JO - The Journal of Physical Chemistry Letters
JF - The Journal of Physical Chemistry Letters
IS - 13
ER -