TY - JOUR
T1 - Intra-luminal thermometry: Is tissue type assignment a necessity for thermal analysis?
T2 - Is tissue type assignment a necessity for thermal analysis?
AU - Fatehi, D.
AU - van der Zee, J.
AU - Wielheesen, D.H.M.
AU - van Wieringen, W.N.
AU - van Rhoon, G.C.
PY - 2006/9/1
Y1 - 2006/9/1
N2 - Introduction: Tissue type assignment, i.e. differentiation tumour from normal tissue, is a normal procedure for interstitial thermometry. In our department, thermometry in patients with a tumour in the lower pelvis is usually restricted to the intra-luminal tracks. It is unknown whether discrimination between normal and tumour tissue is relevant for deep regional hyperthermia thermal dosimetry using only intra-luminal tumour contact and tumour adjacent thermometry. This study has analysed the acquired temperature data in order to answer this question. Patients and methods: Seventy-five patients with locally advanced cervical carcinoma were selected randomly. Patients were treated with a two or three modality combination, i.e. radiotherapy + hyperthermia or radiotherapy + hyperthermia + chemotherapy from October 1997 to September 2003. The first 100 hyperthermia treatments fulfilling the only selection criterion: no displacement of the thermometry catheter along the insertion length during the treatment, were included in the study, resulting in 43 patients with one-to-five treatments/patient (median 2). Using RHyThM (Rotterdam Hyperthermia Thermal Modulator), for each single treatment tissue type, was defined on the basis of information given by a CT scan in radiotherapy position. A step change in the slope of the profile of the first temperature map was identified to verify the insertion length of the catheter. Results: The average T
AB - Introduction: Tissue type assignment, i.e. differentiation tumour from normal tissue, is a normal procedure for interstitial thermometry. In our department, thermometry in patients with a tumour in the lower pelvis is usually restricted to the intra-luminal tracks. It is unknown whether discrimination between normal and tumour tissue is relevant for deep regional hyperthermia thermal dosimetry using only intra-luminal tumour contact and tumour adjacent thermometry. This study has analysed the acquired temperature data in order to answer this question. Patients and methods: Seventy-five patients with locally advanced cervical carcinoma were selected randomly. Patients were treated with a two or three modality combination, i.e. radiotherapy + hyperthermia or radiotherapy + hyperthermia + chemotherapy from October 1997 to September 2003. The first 100 hyperthermia treatments fulfilling the only selection criterion: no displacement of the thermometry catheter along the insertion length during the treatment, were included in the study, resulting in 43 patients with one-to-five treatments/patient (median 2). Using RHyThM (Rotterdam Hyperthermia Thermal Modulator), for each single treatment tissue type, was defined on the basis of information given by a CT scan in radiotherapy position. A step change in the slope of the profile of the first temperature map was identified to verify the insertion length of the catheter. Results: The average T
KW - Cervical cancer
KW - Loco-regional hyperthermia
KW - Temperature monitoring
KW - Tissue type assignment
UR - http://www.scopus.com/inward/record.url?scp=33749031543&partnerID=8YFLogxK
U2 - https://doi.org/10.1080/02656730600773175
DO - https://doi.org/10.1080/02656730600773175
M3 - Article
C2 - 16971367
SN - 0265-6736
VL - 22
SP - 463
EP - 473
JO - International journal of hyperthermia
JF - International journal of hyperthermia
IS - 6
ER -