TY - JOUR
T1 - Intravascular ultrasound radiofrequency analysis after optimal coronary stenting with initial quantitative coronary angiography guidance: An ATHEROREMO sub-study
AU - Sarno, Giovanna
AU - Garg, Scot
AU - Gomez-Lara, Josep
AU - Garcia Garcia, Hector M.
AU - Ligthart, Jurgen
AU - Bruining, Nico
AU - Onuma, Yoshinobu
AU - Witberg, Karen
AU - van Geuns, Robert-Jan
AU - de Boer, Sanneke
AU - Wykrzykowska, Joanna
AU - Schultz, Carl
AU - Duckers, Henricus J.
AU - Regar, Evelyn
AU - de Jaegere, Peter
AU - de Feyter, Pim
AU - van Es, Gerrit Anne
AU - Boersma, Eric
AU - van der Giessen, Wim
AU - Serruys, Patrick W.
PY - 2011/3
Y1 - 2011/3
N2 - Aims: To investigate whether the use of intravascular ultrasound virtual histology (IVUS-VH) leads to any improvements in stent deployment, when performed in patients considered to have had an optimal percutaneous coronary intervention (PCI) by quantitative coronary angiography (QCA). Methods and results: After optimal PCI result (residual stenosis by QCA <30%), IVUS-VH was performed in 100 patients by protocol, with the option to use the information left to the discretion of the operators. Patients were categorised as: Group1 (n=54), where the IVUS-VH findings were used to evaluate the need for further optimisation of the stent deployment; and Group2 (n=46), where the IVUS-VH was documentary such that the stenting results were considered optimal according to QCA. Optimal stent deployment on IVUS-VH was defined as: normal stent expansion, absence of stent malapposition, complete lesion coverage as indicated by a plaque burden (PB%) between 30-40% and necrotic core confluent to the lumen <10% or PB%<30% at the 5 mm proximal and distal to the stent. The first IVUS-VH in all patients demonstrated the achievement of optimal stent deployment, incomplete lesion coverage, stent under-expansion and stent-edge dissection in 60%, 31%, 20% and 8% of patients, respectively. There was no stent malapposition. In Group 1, 25 patients had optimal stent deployment and did not require further intervention, whilst in 29 patients further intervention was needed (additional stent, n= 18; post-dilatation, n=29). Overall optimal stent deployment was finally achieved in 52/54 patients (96%) in Group 1 and 35/46 (76%) of Group 2, p<0.05. Conclusions: IVUS-VH may have a role in facilitating optimal stent implantation and complete lesion coverage. © Europa Edition 2011. All rights reserved.
AB - Aims: To investigate whether the use of intravascular ultrasound virtual histology (IVUS-VH) leads to any improvements in stent deployment, when performed in patients considered to have had an optimal percutaneous coronary intervention (PCI) by quantitative coronary angiography (QCA). Methods and results: After optimal PCI result (residual stenosis by QCA <30%), IVUS-VH was performed in 100 patients by protocol, with the option to use the information left to the discretion of the operators. Patients were categorised as: Group1 (n=54), where the IVUS-VH findings were used to evaluate the need for further optimisation of the stent deployment; and Group2 (n=46), where the IVUS-VH was documentary such that the stenting results were considered optimal according to QCA. Optimal stent deployment on IVUS-VH was defined as: normal stent expansion, absence of stent malapposition, complete lesion coverage as indicated by a plaque burden (PB%) between 30-40% and necrotic core confluent to the lumen <10% or PB%<30% at the 5 mm proximal and distal to the stent. The first IVUS-VH in all patients demonstrated the achievement of optimal stent deployment, incomplete lesion coverage, stent under-expansion and stent-edge dissection in 60%, 31%, 20% and 8% of patients, respectively. There was no stent malapposition. In Group 1, 25 patients had optimal stent deployment and did not require further intervention, whilst in 29 patients further intervention was needed (additional stent, n= 18; post-dilatation, n=29). Overall optimal stent deployment was finally achieved in 52/54 patients (96%) in Group 1 and 35/46 (76%) of Group 2, p<0.05. Conclusions: IVUS-VH may have a role in facilitating optimal stent implantation and complete lesion coverage. © Europa Edition 2011. All rights reserved.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79954557892&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/21330246
U2 - https://doi.org/10.4244/EIJV6I8A169
DO - https://doi.org/10.4244/EIJV6I8A169
M3 - Article
C2 - 21330246
SN - 1774-024X
VL - 6
SP - 977
EP - 984
JO - Eurointervention
JF - Eurointervention
IS - 8
ER -