Is placebo analgesia mediated by endogenous opioids? A systematic review

G. ter Riet; A. J. de Craen; Anthonius de Boer; A. G. Kessels

doi:https://doi.org/10.1016/S0304-3959(98)00057-8

Is placebo analgesia mediated by endogenous opioids? A systematic review

G. ter Riet, A. J. de Craen, Anthonius de Boer, A. G. Kessels

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Research output: Contribution to journal › Review article › Academic › peer-review

101 Citations (Scopus)

Abstract

This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain. Due to their sophisticated designs, these studies probably provide the best evidence that placebo analgesia exists. They also indicate that placebo analgesia is mediated by endogenous opiates. However, there seems to be room for additional studies

Original language	English
Pages (from-to)	273-275
Journal	Pain
Volume	76
Issue number	3
DOIs	https://doi.org/10.1016/S0304-3959(98)00057-8
Publication status	Published - 1998

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https://doi.org/10.1016/S0304-3959(98)00057-8

Cite this

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title = "Is placebo analgesia mediated by endogenous opioids? A systematic review",

abstract = "This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain. Due to their sophisticated designs, these studies probably provide the best evidence that placebo analgesia exists. They also indicate that placebo analgesia is mediated by endogenous opiates. However, there seems to be room for additional studies",

author = "{ter Riet}, G. and {de Craen}, {A. J.} and {de Boer}, Anthonius and Kessels, {A. G.}",

year = "1998",

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AU - ter Riet, G.

AU - de Craen, A. J.

AU - de Boer, Anthonius

AU - Kessels, A. G.

PY - 1998

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AB - This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain. Due to their sophisticated designs, these studies probably provide the best evidence that placebo analgesia exists. They also indicate that placebo analgesia is mediated by endogenous opiates. However, there seems to be room for additional studies

U2 - https://doi.org/10.1016/S0304-3959(98)00057-8

DO - https://doi.org/10.1016/S0304-3959(98)00057-8

M3 - Review article

C2 - 9718245

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VL - 76

SP - 273

EP - 275

JO - Pain

JF - Pain

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