TY - JOUR
T1 - Is the introduction of more advanced radiotherapy techniques for locally-advanced head and neck cancer associated with improved quality of life and reduced symptom burden?
AU - Dahele, Max
AU - Tol, Jim P.
AU - Vergeer, Marije R.
AU - Jansen, Femke
AU - Lissenberg-Witte, Birgit I.
AU - Leemans, C. Rene
AU - Slotman, Ben J.
AU - Verdonck-de Leeuw, Irma M.
AU - Verbakel, Wilko F.A.R.
PY - 2020/10
Y1 - 2020/10
N2 - Technical improvements in head and neck cancer radiotherapy over the last decade have resulted in substantial reductions in dose to organs-at-risk. For a mix of tumors, we saw less xerostomia moving from 3D-conformal to more advanced techniques. For oropharynx-only there were additional improvements, including in global quality-of-life and sticky saliva.
AB - Technical improvements in head and neck cancer radiotherapy over the last decade have resulted in substantial reductions in dose to organs-at-risk. For a mix of tumors, we saw less xerostomia moving from 3D-conformal to more advanced techniques. For oropharynx-only there were additional improvements, including in global quality-of-life and sticky saliva.
KW - Head and neck radiotherapy
KW - Organ at risk sparing
KW - Patient reported outcome
KW - Quality of life
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U2 - https://doi.org/10.1016/j.radonc.2020.08.026
DO - https://doi.org/10.1016/j.radonc.2020.08.026
M3 - Article
C2 - 32890608
SN - 0167-8140
VL - 151
SP - 298
EP - 303
JO - Radiotherapy and oncology
JF - Radiotherapy and oncology
ER -