Joint EANM/SNMMI/ESTRO practice recommendations for the use of 2-[18F]FDG PET/CT external beam radiation treatment planning in lung cancer V1.0

Sofia C. Vaz, Judit A. Adam, Roberto C. Delgado Bolton, Pierre Vera, Wouter van Elmpt, Ken Herrmann, Rodney J. Hicks, Yolande Lievens, Andrea Santos, Heiko Schöder, Bernard Dubray, Dimitris Visvikis, Esther G. C. Troost, Lioe-Fee de Geus-Oei

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)


Purpose: 2-[18F]FDGPET/CT is of utmost importance for radiation treatment (RT) planning and response monitoring in lung cancer patients, in both non-small and small cell lung cancer (NSCLC and SCLC). This topic has been addressed in guidelines composed by experts within the field of radiation oncology. However, up to present, there is no procedural guideline on this subject, with involvement of the nuclear medicine societies. Methods: A literature review was performed, followed by a discussion between a multidisciplinary team of experts in the different fields involved in the RT planning of lung cancer, in order to guide clinical management. The project was led by experts of the two nuclear medicine societies (EANM and SNMMI) and radiation oncology (ESTRO). Results and conclusion: This guideline results from a joint and dynamic collaboration between the relevant disciplines for this topic. It provides a worldwide, state of the art, and multidisciplinary guide to 2-[18F]FDG PET/CT RT planning in NSCLC and SCLC. These practical recommendations describe applicable updates for existing clinical practices, highlight potential flaws, and provide solutions to overcome these as well. Finally, the recent developments considered for future application are also reviewed.
Original languageEnglish
Pages (from-to)1386-1406
Number of pages21
JournalEuropean journal of nuclear medicine and molecular imaging
Issue number4
Early online date2022
Publication statusPublished - 1 Mar 2022


  • CT
  • ESTRO, 2-[ F]FDG PET
  • Lung cancer
  • Planning
  • Radiation therapy
  • Radiotherapy, EANM

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