Keeping Stem Cells in Check: A Hippo Balancing Act

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Abstract

Knowing when to stop proliferation is crucial for any regenerative process. In a recent issue of Nature, Barry et al. (2012) report that the Hippo pathway component YAP negatively regulates Wnt signaling, thereby preventing stem cell overpopulation after a regenerative response in the intestine
Original languageEnglish
Pages (from-to)3-5
JournalCell Stem Cell
Volume12
Issue number1
DOIs
Publication statusPublished - 2013

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