TY - JOUR
T1 - Left bundle branch block after sutureless, transcatheter, and stented biological aortic valve replacement for aortic stenosis
AU - Regeer, Madelien V.
AU - Merkestein, Lisanne R.
AU - de Weger, Arend
AU - Kamperidis, Vasileios
AU - van der Kley, Frank
AU - van Rosendael, Philippe J.
AU - Marsan, Nina Ajmone
AU - Klautz, Robert J. M.
AU - Schalij, Martin J.
AU - Bax, Jeroen J.
AU - Delgado, Victoria
PY - 2017
Y1 - 2017
N2 - Aims: Conventional aortic valve replacement (AVR), sutureless AVR (su-AVR) and transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) are associated with conduction abnormalities. The aim of the present study was to assess the incidence of left bundle branch block (LBBB) after su-AVR and TAVI, in comparison to conventional AVR. Methods and results: A total of 501 patients (mean age 74±8 years, 53% male) without preoperative cardiac conduction disturbances who underwent AVR or TAVI were included in the study. Su-AVR patients and TAVI patients had a higher incidence of new-onset LBBB at hospital discharge (23% and 16%, respectively) compared to patients treated with conventional AVR (4%; p<0.001). On multivariate logistic regression analyses, the type of AVR was independently associated with complete LBBB, after correcting for age, preoperative QRS duration and heart rate (su-AVR and TAVI relative to the reference category conventional AVR: odds ratio [OR] 8.5, 95% confidence interval [CI]: 3.7-19.5; p<0.001, and OR 5.8, 95% CI: 2.4-14.1; p<0.001, respectively). Conclusions: Su-AVR and TAVI were associated with higher risk of developing postoperative LBBB compared to conventional AVR, after adjusting for age, preoperative heart rate and QRS duration.
AB - Aims: Conventional aortic valve replacement (AVR), sutureless AVR (su-AVR) and transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) are associated with conduction abnormalities. The aim of the present study was to assess the incidence of left bundle branch block (LBBB) after su-AVR and TAVI, in comparison to conventional AVR. Methods and results: A total of 501 patients (mean age 74±8 years, 53% male) without preoperative cardiac conduction disturbances who underwent AVR or TAVI were included in the study. Su-AVR patients and TAVI patients had a higher incidence of new-onset LBBB at hospital discharge (23% and 16%, respectively) compared to patients treated with conventional AVR (4%; p<0.001). On multivariate logistic regression analyses, the type of AVR was independently associated with complete LBBB, after correcting for age, preoperative QRS duration and heart rate (su-AVR and TAVI relative to the reference category conventional AVR: odds ratio [OR] 8.5, 95% confidence interval [CI]: 3.7-19.5; p<0.001, and OR 5.8, 95% CI: 2.4-14.1; p<0.001, respectively). Conclusions: Su-AVR and TAVI were associated with higher risk of developing postoperative LBBB compared to conventional AVR, after adjusting for age, preoperative heart rate and QRS duration.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85016056789&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/28106000
U2 - https://doi.org/10.4244/EIJ-D-15-00256
DO - https://doi.org/10.4244/EIJ-D-15-00256
M3 - Article
C2 - 28106000
SN - 1774-024X
VL - 12
SP - 1660
EP - 1666
JO - Eurointervention
JF - Eurointervention
IS - 13
ER -