Limited geographic distribution of the novel cyclovirus CyCV-VN

Van Tan Le; Menno D. de Jong; Van Kinh Nguyen; Vu Trung Nguyen; Walter Taylor; Heiman F. L. Wertheim; Arie van der Ende; Lia van der Hoek; Marta Canuti; Martin Crusat; Soeng Sona; Hanh Uyen Nguyen; Abhishek Giri; Thi Thuy Chinh Bkrong Nguyen; Dang Trung Nghia Ho; Jeremy Farrar; Juliet E. Bryant; Tinh Hien Tran; Van Vinh Chau Nguyen; H. Rogier van Doorn

doi:https://doi.org/10.1038/srep03967

Limited geographic distribution of the novel cyclovirus CyCV-VN

Van Tan Le, Menno D. de Jong, Van Kinh Nguyen, Vu Trung Nguyen, Walter Taylor, Heiman F. L. Wertheim, Arie van der Ende, Lia van der Hoek, Marta Canuti, Martin Crusat, Soeng Sona, Hanh Uyen Nguyen, Abhishek Giri, Thi Thuy Chinh Bkrong Nguyen, Dang Trung Nghia Ho, Jeremy Farrar, Juliet E. Bryant, Tinh Hien Tran, Van Vinh Chau Nguyen, H. Rogier van Doorn

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

A novel cyclovirus, CyCV-VN, was recently identified in cerebrospinal fluid (CSF) from patients with central nervous system (CNS) infections in central and southern Vietnam. To explore the geographic distribution of this novel virus, more than 600 CSF specimens from patients with suspected CNS infections in northern Vietnam, Cambodia, Nepal and The Netherlands were screened for the presence of CyCV-VN but all were negative. Sequence comparison and phylogenetic analysis between CyCV-VN and another novel cyclovirus recently identified in CSF from Malawian patients indicated that these represent distinct cycloviral species, albeit phylogenetically closely related. The data suggest that CyCV-VN has a limited geographic distribution within southern and central Vietnam. Further research is needed to determine the global distribution and diversity of cycloviruses and importantly their possible association with human disease

Original language	English
Pages (from-to)	3967
Journal	Scientific reports
Volume	4
DOIs	https://doi.org/10.1038/srep03967
Publication status	Published - 2014

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Le, V. T., de Jong, M. D., Nguyen, V. K., Nguyen, V. T., Taylor, W., Wertheim, H. F. L., van der Ende, A., van der Hoek, L., Canuti, M., Crusat, M., Sona, S., Nguyen, H. U., Giri, A., Nguyen, T. T. C. B., Ho, D. T. N., Farrar, J., Bryant, J. E., Tran, T. H., Nguyen, V. V. C., & van Doorn, H. R. (2014). Limited geographic distribution of the novel cyclovirus CyCV-VN. Scientific reports, 4, 3967. https://doi.org/10.1038/srep03967

@article{81dfe1d190e54546b14f5900060b5a88,

title = "Limited geographic distribution of the novel cyclovirus CyCV-VN",

abstract = "A novel cyclovirus, CyCV-VN, was recently identified in cerebrospinal fluid (CSF) from patients with central nervous system (CNS) infections in central and southern Vietnam. To explore the geographic distribution of this novel virus, more than 600 CSF specimens from patients with suspected CNS infections in northern Vietnam, Cambodia, Nepal and The Netherlands were screened for the presence of CyCV-VN but all were negative. Sequence comparison and phylogenetic analysis between CyCV-VN and another novel cyclovirus recently identified in CSF from Malawian patients indicated that these represent distinct cycloviral species, albeit phylogenetically closely related. The data suggest that CyCV-VN has a limited geographic distribution within southern and central Vietnam. Further research is needed to determine the global distribution and diversity of cycloviruses and importantly their possible association with human disease",

author = "Le, {Van Tan} and {de Jong}, {Menno D.} and Nguyen, {Van Kinh} and Nguyen, {Vu Trung} and Walter Taylor and Wertheim, {Heiman F. L.} and {van der Ende}, Arie and {van der Hoek}, Lia and Marta Canuti and Martin Crusat and Soeng Sona and Nguyen, {Hanh Uyen} and Abhishek Giri and Nguyen, {Thi Thuy Chinh Bkrong} and Ho, {Dang Trung Nghia} and Jeremy Farrar and Bryant, {Juliet E.} and Tran, {Tinh Hien} and Nguyen, {Van Vinh Chau} and {van Doorn}, {H. Rogier}",

year = "2014",

doi = "https://doi.org/10.1038/srep03967",

language = "English",

volume = "4",

pages = "3967",

journal = "Scientific reports",

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Le, VT, de Jong, MD, Nguyen, VK, Nguyen, VT, Taylor, W, Wertheim, HFL, van der Ende, A , van der Hoek, L, Canuti, M, Crusat, M, Sona, S, Nguyen, HU, Giri, A, Nguyen, TTCB, Ho, DTN, Farrar, J, Bryant, JE, Tran, TH, Nguyen, VVC & van Doorn, HR 2014, 'Limited geographic distribution of the novel cyclovirus CyCV-VN', Scientific reports, vol. 4, pp. 3967. https://doi.org/10.1038/srep03967

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T1 - Limited geographic distribution of the novel cyclovirus CyCV-VN

AU - Le, Van Tan

AU - de Jong, Menno D.

AU - Nguyen, Van Kinh

AU - Nguyen, Vu Trung

AU - Taylor, Walter

AU - Wertheim, Heiman F. L.

AU - van der Ende, Arie

AU - van der Hoek, Lia

AU - Canuti, Marta

AU - Crusat, Martin

AU - Sona, Soeng

AU - Nguyen, Hanh Uyen

AU - Giri, Abhishek

AU - Nguyen, Thi Thuy Chinh Bkrong

AU - Ho, Dang Trung Nghia

AU - Farrar, Jeremy

AU - Bryant, Juliet E.

AU - Tran, Tinh Hien

AU - Nguyen, Van Vinh Chau

AU - van Doorn, H. Rogier

PY - 2014

Y1 - 2014

N2 - A novel cyclovirus, CyCV-VN, was recently identified in cerebrospinal fluid (CSF) from patients with central nervous system (CNS) infections in central and southern Vietnam. To explore the geographic distribution of this novel virus, more than 600 CSF specimens from patients with suspected CNS infections in northern Vietnam, Cambodia, Nepal and The Netherlands were screened for the presence of CyCV-VN but all were negative. Sequence comparison and phylogenetic analysis between CyCV-VN and another novel cyclovirus recently identified in CSF from Malawian patients indicated that these represent distinct cycloviral species, albeit phylogenetically closely related. The data suggest that CyCV-VN has a limited geographic distribution within southern and central Vietnam. Further research is needed to determine the global distribution and diversity of cycloviruses and importantly their possible association with human disease

AB - A novel cyclovirus, CyCV-VN, was recently identified in cerebrospinal fluid (CSF) from patients with central nervous system (CNS) infections in central and southern Vietnam. To explore the geographic distribution of this novel virus, more than 600 CSF specimens from patients with suspected CNS infections in northern Vietnam, Cambodia, Nepal and The Netherlands were screened for the presence of CyCV-VN but all were negative. Sequence comparison and phylogenetic analysis between CyCV-VN and another novel cyclovirus recently identified in CSF from Malawian patients indicated that these represent distinct cycloviral species, albeit phylogenetically closely related. The data suggest that CyCV-VN has a limited geographic distribution within southern and central Vietnam. Further research is needed to determine the global distribution and diversity of cycloviruses and importantly their possible association with human disease

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