@article{b4bc141ad98c4525984a9e3728a1c016,
title = "Lipid profiles in HIV-infected patients receiving combination antiretroviral therapy: Are different antiretroviral drugs associated with different lipid profiles?: Are different antiretroviral drugs associated with different lipid profiles?",
abstract = "Levels of triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), and high-density lipoprotein cholesterol (HDL-c), as well as the TC:HDL-c ratio, were compared in patients receiving different antiretroviral therapy regimens. Patients receiving first-line regimens including protease inhibitors (PIs) had higher TC and TG levels and TC:HDL-c ratios than did antiretroviral-naive patients; patients receiving 2 PIs had higher levels of each lipid. Ritonavir-containing regimens were associated with higher TC and TG levels and TC:HDL-c ratios than were indinavir-containing regimens; however, receipt of nelfinavir was associated with reduced risk of lower HDL-c levels, and receipt of saquinavir was associated with lower TC:HDL-c ratios. Patients receiving non-nucleoside reverse-transcriptase inhibitors had higher levels of TC and LDL-c than did antiretroviral-naive patients, although the risk of having lower HDL-c levels was lower than that in patients receiving a single PI. Efavirenz was associated with higher levels of TC and TG than was nevirapine",
author = "E. Fontas and {van Leth}, F. and Sabin, {C. A.} and N. Friis-M{\o}ller and M. Rickenbach and {d'Arminio Monforte}, A. and O. Kirk and M. Dupon and L. Morfeldt and S. Mateu and K. Petoumenos and W. El-Sadr and {de Wit}, S. and Lundgren, {J. D.} and C. Pradier and P. Reiss and {AUTHOR GROUP} and {de Wolf}, F. and {van der Ven}, E. and S. Zaheri and {van Valkengoed}, I. and R. Meester and H. Weigel and K. Brinkman and P. Frissen and {ten Veen}, J. and M. Hillebrand and {van Dam}, P. and S. Schieveld and J. Mulder and {van Gorp}, E. and P. Meenhorst and {van Eeden}, A. and S. Danner and F. Claessen and R. Perenboom and {Eeftinck Schattenkerk}, {J. K.} and M. Godfried and J. Lange and S. Lowe and {van der Meer}, J. and F. Nellen and K. Pogany and {van der Poll}, T. and J. Prins and T. Ruys and {van Agtmael}, M. and {van der Valk}, M. and F. Wit and {et al}",
year = "2004",
month = mar,
day = "15",
doi = "https://doi.org/10.1086/381783",
language = "English",
volume = "189",
pages = "1056--1074",
journal = "Journal of infectious diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "6",
}