Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

K.J. Gotink; H.J. Broxterman; M. Labots; R.R. de Haas; H. Dekker; R.J. Honeywell; M.A. Rudek; L.V. Beerepoot; R.J.P. Musters; G. Jansen; A.W. Griffioen; Y.G. Assaraf; R. Pili; G.J. Peters; H.M.W. Verheul

doi:https://doi.org/10.1158/1078-0432.CCR-11-1667

Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

K.J. Gotink, H.J. Broxterman, M. Labots, R.R. de Haas, H. Dekker, R.J. Honeywell, M.A. Rudek, L.V. Beerepoot, R.J.P. Musters, G. Jansen, A.W. Griffioen, Y.G. Assaraf, R. Pili, G.J. Peters, H.M.W. Verheul

Research output: Contribution to journal › Article › Academic › peer-review

262 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	7337-7346
Journal	Clinical Cancer Research
Volume	17
Issue number	23
DOIs	https://doi.org/10.1158/1078-0432.CCR-11-1667
Publication status	Published - 2011

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https://doi.org/10.1158/1078-0432.CCR-11-1667

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Gotink, K. J., Broxterman, H. J., Labots, M., de Haas, R. R., Dekker, H., Honeywell, R. J., Rudek, M. A., Beerepoot, L. V., Musters, R. J. P., Jansen, G., Griffioen, A. W., Assaraf, Y. G., Pili, R., Peters, G. J., & Verheul, H. M. W. (2011). Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance. Clinical Cancer Research, 17(23), 7337-7346. https://doi.org/10.1158/1078-0432.CCR-11-1667

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author = "K.J. Gotink and H.J. Broxterman and M. Labots and {de Haas}, R.R. and H. Dekker and R.J. Honeywell and M.A. Rudek and L.V. Beerepoot and R.J.P. Musters and G. Jansen and A.W. Griffioen and Y.G. Assaraf and R. Pili and G.J. Peters and H.M.W. Verheul",

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Gotink, KJ, Broxterman, HJ, Labots, M, de Haas, RR, Dekker, H, Honeywell, RJ, Rudek, MA, Beerepoot, LV, Musters, RJP, Jansen, G , Griffioen, AW, Assaraf, YG, Pili, R, Peters, GJ & Verheul, HMW 2011, 'Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance', Clinical Cancer Research, vol. 17, no. 23, pp. 7337-7346. https://doi.org/10.1158/1078-0432.CCR-11-1667

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T1 - Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

AU - Gotink, K.J.

AU - Broxterman, H.J.

AU - Labots, M.

AU - de Haas, R.R.

AU - Dekker, H.

AU - Honeywell, R.J.

AU - Rudek, M.A.

AU - Beerepoot, L.V.

AU - Musters, R.J.P.

AU - Jansen, G.

AU - Griffioen, A.W.

AU - Assaraf, Y.G.

AU - Pili, R.

AU - Peters, G.J.

AU - Verheul, H.M.W.

PY - 2011

Y1 - 2011

U2 - https://doi.org/10.1158/1078-0432.CCR-11-1667

DO - https://doi.org/10.1158/1078-0432.CCR-11-1667

M3 - Article

C2 - 21980135

SN - 1078-0432

VL - 17

SP - 7337

EP - 7346

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 23

ER -