TY - JOUR
T1 - Macro EMG follow-up study in post-poliomyelitis patients
AU - Ivanyi, B.
AU - Ongerboer de Visser, B. W.
AU - Nelemans, P. J.
AU - de Visser, M.
PY - 1994
Y1 - 1994
N2 - We investigated the muscle strength and motor unit (MU) territory of five patients with postpolio syndrome (PPS), six stable patients with prior poliomyelitis, and five healthy volunteers. The MU territory was assessed by measuring amplitudes of motor unit potentials (MUPs) recorded by the macro EMG technique. The investigations were repeated after 11-20 months (mean 15.6). The macro MUP amplitudes in both patient groups were markedly increased (P = 0.02). However, no statistical difference was found between the two groups in the initial amplitude values. Macro MUP amplitudes obtained on repeated examinations did not differ significantly from the initial macro MUP amplitudes in any of the three groups. In three individual PPS patients, a decline in muscle strength on the follow-up study was documented, providing the diagnosis of post-poliomyelitis muscular atrophy (PPMA). The three PPMA patients had the highest initial macro MUPs. Two of them showed a decrease in macro MUP amplitudes on follow-up. These findings suggest that a later breakdown of oversized MUs may play a role in the pathogenesis of PPMA
AB - We investigated the muscle strength and motor unit (MU) territory of five patients with postpolio syndrome (PPS), six stable patients with prior poliomyelitis, and five healthy volunteers. The MU territory was assessed by measuring amplitudes of motor unit potentials (MUPs) recorded by the macro EMG technique. The investigations were repeated after 11-20 months (mean 15.6). The macro MUP amplitudes in both patient groups were markedly increased (P = 0.02). However, no statistical difference was found between the two groups in the initial amplitude values. Macro MUP amplitudes obtained on repeated examinations did not differ significantly from the initial macro MUP amplitudes in any of the three groups. In three individual PPS patients, a decline in muscle strength on the follow-up study was documented, providing the diagnosis of post-poliomyelitis muscular atrophy (PPMA). The three PPMA patients had the highest initial macro MUPs. Two of them showed a decrease in macro MUP amplitudes on follow-up. These findings suggest that a later breakdown of oversized MUs may play a role in the pathogenesis of PPMA
U2 - https://doi.org/10.1007/BF00920572
DO - https://doi.org/10.1007/BF00920572
M3 - Article
C2 - 7897450
SN - 0340-5354
VL - 242
SP - 37
EP - 40
JO - Journal of neurology
JF - Journal of neurology
IS - 1
ER -