Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption

Shyama U. Tetar, Anna M. E. Bruynzeel, Lisa Verweij, Omar Bohoudi, Berend J. Slotman, Tezontl Rosario, Miguel A. Palacios, Frank J. Lagerwaard

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6 Citations (Scopus)


Magnetic resonance-guided radiotherapy with daily plan adaptation for intermediate- and high-risk prostate cancer is time and labor intensive. Fifty adapted plans with 3 mm planning target volume (PTV)-margin were compared with non-adapted plans using 3 or 5 mm margins. Adequate (V95% ≥ 95%) prostate coverage was achieved in 49 fractions with 5 mm PTV without plan adaptation, however, coverage of the seminal vesicles (SV) was insufficient in 15 of 50 fractions. There was no insufficient coverage for prostate and SV using plan adaptation with 3 mm. Hence, daily adaptation is recommended to obtain adequate SV-coverage when using 3 mm PTV.
Original languageEnglish
Pages (from-to)92-96
Number of pages5
JournalPhysics and Imaging in Radiation Oncology
Publication statusPublished - 1 Jul 2022


  • Dosimetry
  • Interfraction motion
  • MR-guided radiotherapy
  • Plan adaptation
  • Prostate cancer
  • Seminal vesicles

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