TY - JOUR
T1 - Malaria after international travel: a GeoSentinel analysis, 2003-2016
AU - Angelo, Kristina M.
AU - Libman, Michael
AU - Caumes, Eric
AU - Hamer, Davidson H.
AU - Kain, Kevin C.
AU - Leder, Karin
AU - Grobusch, Martin P.
AU - Hagmann, Stefan H.
AU - Kozarsky, Phyllis
AU - Lalloo, David G.
AU - Lim, Poh-Lian
AU - Patimeteeporn, Calvin
AU - Gautret, Philippe
AU - Odolini, Silvia
AU - Chappuis, François
AU - Esposito, Douglas H.
AU - AUTHOR GROUP
AU - Javelle, Emilie
AU - Castelli, Francesco
AU - Matteelli, Alberto
AU - Perignon, Alice
AU - Rothe, Camilla
AU - Rapp, Christoph
AU - Ficko, Cecile
AU - Schwartz, Eli
AU - von Sonnenburg, Frank
AU - Piyaphanee, Watcharapong
AU - Silachamroon, Udomsak
AU - Boggild, Andrea
AU - van Genderen, Perry
AU - Torresi, Joe
AU - Jensenius, Mogens
AU - Kanagawa, Shuzo
AU - Kato, Yasuyuki
AU - Yansouni, Cedric
AU - McCarthy, Anne
AU - Kelly, Paul
AU - Goorhuis, Bram
AU - López-Vélez, Rogelio
AU - Norman, Francesco
AU - Mendelson, Marc
AU - Vincent, Peter
AU - Gkrania-Klotsas, Effrossyni
AU - Warne, Ben
AU - Malvy, Denis
AU - Duvignaud, Alexandre
AU - Bottieau, Emanuel
AU - Clerinx, Joannes
AU - Coyle, Christina
AU - Àsgeirsson, Hilmer
AU - Glans, Hedvig
PY - 2017
Y1 - 2017
N2 - More than 30,000 malaria cases are reported annually among international travellers. Despite improvements in malaria control, malaria continues to threaten travellers due to inaccurate perception of risk and sub-optimal pre-travel preparation. Records with a confirmed malaria diagnosis after travel from January 2003 to July 2016 were obtained from GeoSentinel, a global surveillance network of travel and tropical medicine providers that monitors travel-related morbidity. Records were excluded if exposure country was missing or unascertainable or if there was a concomitant acute diagnosis unrelated to malaria. Records were analyzed to describe the demographic and clinical characteristics of international travellers with malaria. There were 5689 travellers included; 325 were children <18 years. More than half (53%) were visiting friends and relatives (VFRs). Most (83%) were exposed in sub-Saharan Africa. The median trip duration was 32 days (interquartile range 20-75); 53% did not have a pre-travel visit. More than half (62%) were hospitalized; children were hospitalized more frequently than adults (73 and 62%, respectively). Ninety-two per cent had a single Plasmodium species diagnosis, most frequently Plasmodium falciparum (4011; 76%). Travellers with P. falciparum were most frequently VFRs (60%). More than 40% of travellers with a trip duration ≤7 days had Plasmodium vivax. There were 444 (8%) travellers with severe malaria; 31 children had severe malaria. Twelve travellers died. Malaria remains a serious threat to international travellers. Efforts must focus on preventive strategies aimed on children and VFRs, and chemoprophylaxis access and preventive measure adherence should be emphasized
AB - More than 30,000 malaria cases are reported annually among international travellers. Despite improvements in malaria control, malaria continues to threaten travellers due to inaccurate perception of risk and sub-optimal pre-travel preparation. Records with a confirmed malaria diagnosis after travel from January 2003 to July 2016 were obtained from GeoSentinel, a global surveillance network of travel and tropical medicine providers that monitors travel-related morbidity. Records were excluded if exposure country was missing or unascertainable or if there was a concomitant acute diagnosis unrelated to malaria. Records were analyzed to describe the demographic and clinical characteristics of international travellers with malaria. There were 5689 travellers included; 325 were children <18 years. More than half (53%) were visiting friends and relatives (VFRs). Most (83%) were exposed in sub-Saharan Africa. The median trip duration was 32 days (interquartile range 20-75); 53% did not have a pre-travel visit. More than half (62%) were hospitalized; children were hospitalized more frequently than adults (73 and 62%, respectively). Ninety-two per cent had a single Plasmodium species diagnosis, most frequently Plasmodium falciparum (4011; 76%). Travellers with P. falciparum were most frequently VFRs (60%). More than 40% of travellers with a trip duration ≤7 days had Plasmodium vivax. There were 444 (8%) travellers with severe malaria; 31 children had severe malaria. Twelve travellers died. Malaria remains a serious threat to international travellers. Efforts must focus on preventive strategies aimed on children and VFRs, and chemoprophylaxis access and preventive measure adherence should be emphasized
U2 - https://doi.org/10.1186/s12936-017-1936-3
DO - https://doi.org/10.1186/s12936-017-1936-3
M3 - Article
C2 - 28728595
SN - 1475-2875
VL - 16
SP - 293
JO - Malaria journal
JF - Malaria journal
IS - 1
ER -