Malignant melanoma as second malignant neoplasm in long-term childhood cancer survivors: A systematic review

Katja I. Braam; Annelies Overbeek; Gertjan J. L. Kaspers; Cecile M. Ronckers; Annette Y. N. Schouten-van Meeteren; Eline van Dulmen-den Broeder; Margreet A. Veening

doi:https://doi.org/10.1002/pbc.24023

Malignant melanoma as second malignant neoplasm in long-term childhood cancer survivors: A systematic review

Katja I. Braam, Annelies Overbeek, Gertjan J. L. Kaspers, Cecile M. Ronckers, Annette Y. N. Schouten-van Meeteren, Eline van Dulmen-den Broeder, Margreet A. Veening

Research output: Contribution to journal › Review article › Academic › peer-review

29 Citations (Scopus)

Abstract

This systematic review provides information on malignant melanoma as second malignant neoplasm (SMN) after childhood cancer and evaluates its risk factors. Study reports describing incidences of SMN and malignant melanoma as SMN in a population of childhood cancer survivors (CCS) were included. Of 151,575 CCS, 4,010 (2.6%) children developed an SMN, 212 of which were melanoma (5.3% or 0.14% of all CCS). The following risk factors for malignant melanoma as SMN were identified: radiotherapy, or the combination alkylating agents and anti-mitotic drugs. Melanomas are most frequently observed after Hodgkin disease, hereditary retinoblastoma, soft tissue sarcoma, and gonadal tumors. Pediatr Blood Cancer (C) 2012 Wiley Periodicals, Inc

Original language	English
Pages (from-to)	665-674
Journal	Pediatric blood & cancer
Volume	58
Issue number	5
DOIs	https://doi.org/10.1002/pbc.24023
Publication status	Published - 2012

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https://doi.org/10.1002/pbc.24023

Cite this

@article{284ae2ccb4b544aab2b3317456296794,

title = "Malignant melanoma as second malignant neoplasm in long-term childhood cancer survivors: A systematic review",

abstract = "This systematic review provides information on malignant melanoma as second malignant neoplasm (SMN) after childhood cancer and evaluates its risk factors. Study reports describing incidences of SMN and malignant melanoma as SMN in a population of childhood cancer survivors (CCS) were included. Of 151,575 CCS, 4,010 (2.6%) children developed an SMN, 212 of which were melanoma (5.3% or 0.14% of all CCS). The following risk factors for malignant melanoma as SMN were identified: radiotherapy, or the combination alkylating agents and anti-mitotic drugs. Melanomas are most frequently observed after Hodgkin disease, hereditary retinoblastoma, soft tissue sarcoma, and gonadal tumors. Pediatr Blood Cancer (C) 2012 Wiley Periodicals, Inc",

author = "Braam, {Katja I.} and Annelies Overbeek and Kaspers, {Gertjan J. L.} and Ronckers, {Cecile M.} and {Schouten-van Meeteren}, {Annette Y. N.} and {van Dulmen-den Broeder}, Eline and Veening, {Margreet A.}",

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T1 - Malignant melanoma as second malignant neoplasm in long-term childhood cancer survivors: A systematic review

AU - Braam, Katja I.

AU - Overbeek, Annelies

AU - Kaspers, Gertjan J. L.

AU - Ronckers, Cecile M.

AU - Schouten-van Meeteren, Annette Y. N.

AU - van Dulmen-den Broeder, Eline

AU - Veening, Margreet A.

PY - 2012

Y1 - 2012

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AB - This systematic review provides information on malignant melanoma as second malignant neoplasm (SMN) after childhood cancer and evaluates its risk factors. Study reports describing incidences of SMN and malignant melanoma as SMN in a population of childhood cancer survivors (CCS) were included. Of 151,575 CCS, 4,010 (2.6%) children developed an SMN, 212 of which were melanoma (5.3% or 0.14% of all CCS). The following risk factors for malignant melanoma as SMN were identified: radiotherapy, or the combination alkylating agents and anti-mitotic drugs. Melanomas are most frequently observed after Hodgkin disease, hereditary retinoblastoma, soft tissue sarcoma, and gonadal tumors. Pediatr Blood Cancer (C) 2012 Wiley Periodicals, Inc

U2 - https://doi.org/10.1002/pbc.24023

DO - https://doi.org/10.1002/pbc.24023

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