TY - JOUR
T1 - Measurements of wavelength dependent scattering and backscattering coefficients by low-coherence spectroscopy
AU - Bosschaart, N.
AU - Faber, D.J.
AU - van Leeuwen, T.G.
AU - Aalders, M.C.G.
PY - 2011
Y1 - 2011
N2 - Quantitative measurements of scattering properties are invaluable for optical techniques in medicine. However, noninvasive, quantitative measurements of scattering properties over a large wavelength range remain challenging. We introduce low-coherence spectroscopy as a noninvasive method to locally and simultaneously measure scattering mu(s) and backscattering mu(b) coefficients from 480 to 700 nm with 8 nm spectral resolution. The method is tested on media with varying scattering properties (as = 1 to 34 mm(-1) and mu(b) = 2.10(-6) to 2.10(-3) mm(-1)), containing different sized polystyrene spheres. The results are in excellent agreement with Mie theory. (C) 2011 society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3553005]
AB - Quantitative measurements of scattering properties are invaluable for optical techniques in medicine. However, noninvasive, quantitative measurements of scattering properties over a large wavelength range remain challenging. We introduce low-coherence spectroscopy as a noninvasive method to locally and simultaneously measure scattering mu(s) and backscattering mu(b) coefficients from 480 to 700 nm with 8 nm spectral resolution. The method is tested on media with varying scattering properties (as = 1 to 34 mm(-1) and mu(b) = 2.10(-6) to 2.10(-3) mm(-1)), containing different sized polystyrene spheres. The results are in excellent agreement with Mie theory. (C) 2011 society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3553005]
U2 - https://doi.org/10.1117/1.3553005
DO - https://doi.org/10.1117/1.3553005
M3 - Article
C2 - 21456858
SN - 1083-3668
VL - 16
SP - 030503
JO - Journal of biomedical optics
JF - Journal of biomedical optics
IS - 3
M1 - 030503
ER -