TY - JOUR
T1 - Measuring health-related quality of life in colorectal cancer patients
T2 - systematic review of measurement properties of the EORTC QLQ-CR29
AU - van der Hout, Anja
AU - Neijenhuijs, Koen I.
AU - Jansen, Femke
AU - van Uden-Kraan, Cornelia F.
AU - Aaronson, Neil K.
AU - Groenvold, Mogens
AU - Holzner, Bernhard
AU - Terwee, Caroline B.
AU - van de Poll-Franse, Lonneke V.
AU - Cuijpers, Pim
AU - Verdonck-de Leeuw, Irma M.
N1 - Publisher Copyright: © 2019, The Author(s). Copyright: Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.
AB - INTRODUCTION: The EORTC QLQ-CR29 is a patient-reported outcome measure to evaluate health-related quality of life among colorectal cancer patients in research and clinical practice. The aim of this systematic review was to investigate whether the initial positive results regarding the measurement properties of the QLQ-CR29 are confirmed in subsequent studies.METHODS: A systematic search of Embase, Medline, PsycINFO, and Web of Science was conducted to identify studies investigating the measurement properties of the QLQ-CR29 published up to January 2019. For the 11 included studies, data were extracted, methodological quality was assessed, results were synthesized, and evidence was graded according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology on the measurement properties: structural validity, internal consistency, reliability, measurement error, construct validity (hypothesis testing, including known-group comparison, convergent and divergent validity), cross-cultural validity, and responsiveness.RESULTS: Internal consistency was rated as "sufficient," with low evidence. Reliability was rated as "insufficient," with moderate evidence. Construct validity (hypothesis testing; known-group comparison, convergent and divergent validity) was rated as "inconsistent," with moderate evidence. Structural validity, measurement error, and responsiveness were rated as "indeterminate" and could therefore not be graded.CONCLUSION: This review indicates that current evidence supporting the measurement properties of the QLQ-CR29 is limited. Additionally, better quality research is needed, taking into account the COSMIN methodology.
KW - Colorectal Neoplasms/psychology
KW - Colorectal cancer
KW - EORTC QLQ-CR29
KW - Health-related quality of life
KW - Humans
KW - Measurement property
KW - Patient-reported outcome measure (PROM)
KW - Psychometrics/methods
KW - Quality of Life/psychology
KW - Reproducibility of Results
KW - Surveys and Questionnaires
KW - Systematic review
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UR - https://pure.uva.nl/ws/files/51390488/520_2019_4764_MOESM1_ESM.docx
UR - https://pure.uva.nl/ws/files/51390490/520_2019_4764_MOESM2_ESM.docx
U2 - https://doi.org/10.1007/s00520-019-04764-7
DO - https://doi.org/10.1007/s00520-019-04764-7
M3 - Review article
C2 - 30982095
SN - 0941-4355
VL - 27
SP - 2395
EP - 2412
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer
IS - 7
ER -
