Melk-alkalisyndroom

Translated title of the contribution: Milk-alkali syndrome: a careful history is crucial in diagnosing hypercalcemia

Research output: Contribution to journalArticleProfessional

Abstract

BACKGROUND: Milk-alkali syndrome is a rare cause of hypercalcemia in the Netherlands, due to ingestion of large amounts of calcium and absorbable alkali. CASE DESCRIPTION: A 38-year-old female patient was admitted with severe stomach pain, vomiting and weight loss. Laboratory results showed hypercalcemia and acute kidney injury. We initially suspected that the hypercalcemia was related to primary hyperparathyroidism, a malignancy with bone metastasis or a granulomatous disease. Gastroduodenoscopy, however, revealed a duodenal ulcer, which turned out to be Helicobacter pylori-related. A thorough history revealed that the patient had consumed large amounts of milk and antacids to relieve symptoms of heartburn. In light of this history, milk-alkali syndrome was diagnosed. CONCLUSION: The case aims to underline the importance of a thorough history in patients with hypercalcemia. The use of over-the-counter medications and dairy products should be evaluated in all patients presenting with hypercalcemia.
Translated title of the contributionMilk-alkali syndrome: a careful history is crucial in diagnosing hypercalcemia
Original languageDutch
JournalNederlands Tijdschrift voor Geneeskunde
Volume167
Publication statusPublished - 6 Sept 2023

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