Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages

M.L.H. Vlaming; E. van Duijn; M.R. Dillingh; R. Brands; A.D. Windhorst; N.H. Hendrikse; S. Bosgra; J. Burggraaf; M.C. Koning; A. Fidder; J.A.J. Mocking; H. Sandman; R.A.F. de Ligt; B.O. Fabriek; W.J. Pasman; W. Seinen; T. Alves; M. Carrondo; C. Peixoto; P.A.M. Peeters; W.H.J. Vaes

doi:https://doi.org/10.1002/cpt.131

Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages

M.L.H. Vlaming, E. van Duijn, M.R. Dillingh, R. Brands, A.D. Windhorst, N.H. Hendrikse, S. Bosgra, J. Burggraaf, M.C. Koning, A. Fidder, J.A.J. Mocking, H. Sandman, R.A.F. de Ligt, B.O. Fabriek, W.J. Pasman, W. Seinen, T. Alves, M. Carrondo, C. Peixoto, P.A.M. PeetersW.H.J. Vaes

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	196-204
Journal	Clinical Pharmacology & Therapeutics
Volume	98
Issue number	2
DOIs	https://doi.org/10.1002/cpt.131
Publication status	Published - 2015

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https://doi.org/10.1002/cpt.131

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Vlaming, M. L. H., van Duijn, E., Dillingh, M. R., Brands, R., Windhorst, A. D., Hendrikse, N. H., Bosgra, S., Burggraaf, J., Koning, M. C., Fidder, A., Mocking, J. A. J., Sandman, H., de Ligt, R. A. F., Fabriek, B. O., Pasman, W. J., Seinen, W., Alves, T., Carrondo, M., Peixoto, C., ... Vaes, W. H. J. (2015). Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages. Clinical Pharmacology & Therapeutics, 98(2), 196-204. https://doi.org/10.1002/cpt.131

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Vlaming, MLH, van Duijn, E, Dillingh, MR, Brands, R, Windhorst, AD , Hendrikse, NH, Bosgra, S, Burggraaf, J, Koning, MC, Fidder, A, Mocking, JAJ, Sandman, H, de Ligt, RAF, Fabriek, BO, Pasman, WJ, Seinen, W, Alves, T, Carrondo, M, Peixoto, C, Peeters, PAM & Vaes, WHJ 2015, 'Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages', Clinical Pharmacology & Therapeutics, vol. 98, no. 2, pp. 196-204. https://doi.org/10.1002/cpt.131

TY - JOUR

T1 - Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages

AU - Vlaming, M.L.H.

AU - van Duijn, E.

AU - Dillingh, M.R.

AU - Brands, R.

AU - Windhorst, A.D.

AU - Hendrikse, N.H.

AU - Bosgra, S.

AU - Burggraaf, J.

AU - Koning, M.C.

AU - Fidder, A.

AU - Mocking, J.A.J.

AU - Sandman, H.

AU - de Ligt, R.A.F.

AU - Fabriek, B.O.

AU - Pasman, W.J.

AU - Seinen, W.

AU - Alves, T.

AU - Carrondo, M.

AU - Peixoto, C.

AU - Peeters, P.A.M.

AU - Vaes, W.H.J.

PY - 2015

Y1 - 2015

U2 - https://doi.org/10.1002/cpt.131

DO - https://doi.org/10.1002/cpt.131

M3 - Article

C2 - 25869840

SN - 0009-9236

VL - 98

SP - 196

EP - 204

JO - Clinical Pharmacology & Therapeutics

JF - Clinical Pharmacology & Therapeutics

IS - 2

ER -