Abstract
In this issue of Blood, Mraz et al show that microRNA-150 (miR-150) is the most abundantly expressed miR in chronic lymphocytic leukemia (CLL) and affects the threshold for B-cell receptor (BCR) signaling by repressing expression levels of GAB1 and FOXP1. This functional link might explain the described association between expression levels of miR-150 and prognosis.(1)
| Original language | English |
|---|---|
| Pages (from-to) | 2-4 |
| Journal | Blood |
| Volume | 124 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2014 |